# Osteoarthritis Treatment and Mechanisms

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/osteoarthritis-treatment-and-mechanisms-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 2,775,950 |
| Description | This cluster of papers focuses on the pathophysiology of osteoarthritis, with an emphasis on cartilage degradation, inflammation, joint mechanics, and potential therapeutic approaches such as cartilage regeneration using mesenchymal stem cells. It also covers the role of chondrocytes, matrix metalloproteinases, and synovitis in the development and progression of osteoarthritis. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | https://openalex.org/T10105 |
| Works | 126,880 |

## Topic researchers

Showing 12 of 20.

- [Simon I Hay](https://scholariq.org/researchers/simon-i-hay/)
- [George Davey Smith](https://scholariq.org/researchers/george-davey-smith/)
- [Theo Vos](https://scholariq.org/researchers/theo-vos/)
- [Ali H. Mokdad](https://scholariq.org/researchers/ali-h-mokdad/)
- [Jost B. Jonas](https://scholariq.org/researchers/jost-b-jonas/)
- [Cyrus Cooper](https://scholariq.org/researchers/cyrus-cooper/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)
- [Hermann Brenner](https://scholariq.org/researchers/hermann-brenner/)
- [Matthias Egger](https://scholariq.org/researchers/matthias-egger/)
- [John P. A. Ioannidis](https://scholariq.org/researchers/john-p-a-ioannidis/)
- [Gordon Guyatt](https://scholariq.org/researchers/gordon-guyatt/)
- [Gonçalo R. Abecasis](https://scholariq.org/researchers/goncalo-r-abecasis/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
