# Pain Mechanisms and Treatments

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/pain-mechanisms-and-treatments/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the mechanisms, diagnosis, and treatment of neuropathic pain, focusing on central sensitization, neuroinflammation, glial activation, and the modulation of pain perception. It covers topics such as nociception, neuronal plasticity, chronic pain, hyperalgesia, and diabetic neuropathy. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10196 |
| Works | 408 |

## Topic papers all

Showing 15 of 408.

- [Depression and Pain Comorbidity](https://scholariq.org/papers/depression-and-pain-comorbidity/)
- [Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations](https://scholariq.org/papers/interpreting-the-clinical-importance-of-treatment-outcomes-in-chronic-pain/)
- [Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings](https://scholariq.org/papers/sex-gender-and-pain-a-review-of-recent-clinical-and-experimental-findings/)
- [Functional imaging of brain responses to pain. A review and meta-analysis (2000)](https://scholariq.org/papers/functional-imaging-of-brain-responses-to-pain-a-review-and-meta-analysis-2000/)
- [Sex differences in pain: a brief review of clinical and experimental findings](https://scholariq.org/papers/sex-differences-in-pain-a-brief-review-of-clinical-and-experimental-findings/)
- [Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome](https://scholariq.org/papers/activated-mast-cells-in-proximity-to-colonic-nerves-correlate-with-abdominal/)
- [A Practical Two-Step Quantitative Clinical and Electrophysiological Assessment for the Diagnosis and Staging of Diabetic Neuropathy](https://scholariq.org/papers/a-practical-two-step-quantitative-clinical-and-electrophysiological-assessment/)
- [Sex differences in the perception of noxious experimental stimuli: a meta-analysis](https://scholariq.org/papers/sex-differences-in-the-perception-of-noxious-experimental-stimuli-a-meta/)
- [Pain Intensity Processing Within the Human Brain: A Bilateral, Distributed Mechanism](https://scholariq.org/papers/pain-intensity-processing-within-the-human-brain-a-bilateral-distributed/)
- [Acupuncture for Chronic Pain](https://scholariq.org/papers/acupuncture-for-chronic-pain/)
- [Imaging how attention modulates pain in humans using functional MRI](https://scholariq.org/papers/imaging-how-attention-modulates-pain-in-humans-using-functional-mri/)
- [Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis](https://scholariq.org/papers/acupuncture-for-chronic-pain-update-of-an-individual-patient-data-meta-analysis/)
- [Exacerbation of Pain by Anxiety Is Associated with Activity in a Hippocampal Network](https://scholariq.org/papers/exacerbation-of-pain-by-anxiety-is-associated-with-activity-in-a-hippocampal/)
- [Epidemiology of Peripheral Neuropathy and Lower Extremity Disease in Diabetes](https://scholariq.org/papers/epidemiology-of-peripheral-neuropathy-and-lower-extremity-disease-in-diabetes/)
- [Mast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome](https://scholariq.org/papers/mast-cell-dependent-excitation-of-visceral-nociceptive-sensory-neurons-in/)

## Topic primary papers

Showing 15 of 183.

- [Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings](https://scholariq.org/papers/sex-gender-and-pain-a-review-of-recent-clinical-and-experimental-findings/)
- [Functional imaging of brain responses to pain. A review and meta-analysis (2000)](https://scholariq.org/papers/functional-imaging-of-brain-responses-to-pain-a-review-and-meta-analysis-2000/)
- [A Practical Two-Step Quantitative Clinical and Electrophysiological Assessment for the Diagnosis and Staging of Diabetic Neuropathy](https://scholariq.org/papers/a-practical-two-step-quantitative-clinical-and-electrophysiological-assessment/)
- [Sex differences in the perception of noxious experimental stimuli: a meta-analysis](https://scholariq.org/papers/sex-differences-in-the-perception-of-noxious-experimental-stimuli-a-meta/)
- [Pain Intensity Processing Within the Human Brain: A Bilateral, Distributed Mechanism](https://scholariq.org/papers/pain-intensity-processing-within-the-human-brain-a-bilateral-distributed/)
- [Exacerbation of Pain by Anxiety Is Associated with Activity in a Hippocampal Network](https://scholariq.org/papers/exacerbation-of-pain-by-anxiety-is-associated-with-activity-in-a-hippocampal/)
- [Pregabalin for acute and chronic pain in adults](https://scholariq.org/papers/pregabalin-for-acute-and-chronic-pain-in-adults/)
- [The Prevalence, Severity, and Impact of Painful Diabetic Peripheral Neuropathy in Type 2 Diabetes](https://scholariq.org/papers/the-prevalence-severity-and-impact-of-painful-diabetic-peripheral-neuropathy-in/)
- [Painful Temporomandibular Disorder](https://scholariq.org/papers/painful-temporomandibular-disorder/)
- [A Meta-Analytic Review of the Hypoalgesic Effects of Exercise](https://scholariq.org/papers/a-meta-analytic-review-of-the-hypoalgesic-effects-of-exercise/)
- [Quadriceps Arthrogenic Muscle Inhibition: Neural Mechanisms and Treatment Perspectives](https://scholariq.org/papers/quadriceps-arthrogenic-muscle-inhibition-neural-mechanisms-and-treatment/)
- [Haemodynamic brain responses to acute pain in humans](https://scholariq.org/papers/haemodynamic-brain-responses-to-acute-pain-in-humans/)
- [Conditioned Pain Modulation in Populations With Chronic Pain: A Systematic Review and Meta-Analysis](https://scholariq.org/papers/conditioned-pain-modulation-in-populations-with-chronic-pain-a-systematic-review/)
- [Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study](https://scholariq.org/papers/electrical-stimulation-of-motor-cortex-for-pain-control-a-combined-pet-scan-and/)
- [Synaptic Plasticity in Spinal Lamina I Projection Neurons That Mediate Hyperalgesia](https://scholariq.org/papers/synaptic-plasticity-in-spinal-lamina-i-projection-neurons-that-mediate/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.