# Pancreatic function and diabetes

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/pancreatic-function-and-diabetes/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the dysfunction and regeneration of pancreatic islets, particularly related to ß-cell deficit, insulin secretion, diabetes mellitus, islet transplantation, glucose homeostasis, stem cell differentiation, oxidative stress, and pancreas development. The research covers various aspects of pancreatic islet biology and potential therapeutic approaches for addressing islet dysfunction in diabetes. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10839 |
| Works | 639 |

## Topic papers all

Showing 15 of 639.

- [Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes](https://scholariq.org/papers/canagliflozin-and-cardiovascular-and-renal-events-in-type-2-diabetes/)
- [Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction](https://scholariq.org/papers/dapagliflozin-in-patients-with-heart-failure-and-reduced-ejection-fraction/)
- [Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes](https://scholariq.org/papers/dapagliflozin-and-cardiovascular-outcomes-in-type-2-diabetes/)
- [Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy](https://scholariq.org/papers/canagliflozin-and-renal-outcomes-in-type-2-diabetes-and-nephropathy/)
- [Mechanisms linking obesity to insulin resistance and type 2 diabetes](https://scholariq.org/papers/mechanisms-linking-obesity-to-insulin-resistance-and-type-2-diabetes/)
- [Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen](https://scholariq.org/papers/islet-transplantation-in-seven-patients-with-type-1-diabetes-mellitus-using-a/)
- [Empagliflozin in Heart Failure with a Preserved Ejection Fraction](https://scholariq.org/papers/empagliflozin-in-heart-failure-with-a-preserved-ejection-fraction/)
- [Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range](https://scholariq.org/papers/clinical-targets-for-continuous-glucose-monitoring-data-interpretation/)
- [Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes](https://scholariq.org/papers/empagliflozin-and-progression-of-kidney-disease-in-type-2-diabetes/)
- [SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials](https://scholariq.org/papers/sglt2-inhibitors-for-primary-and-secondary-prevention-of-cardiovascular-and/)
- [Type 2 diabetes](https://scholariq.org/papers/type-2-diabetes/)
- [Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes](https://scholariq.org/papers/variant-of-transcription-factor-7-like-2-tcf7l2-gene-confers-risk-of-type-2/)
- [New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk](https://scholariq.org/papers/new-genetic-loci-implicated-in-fasting-glucose-homeostasis-and-their-impact-on/)
- [The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes](https://scholariq.org/papers/the-relative-contributions-of-insulin-resistance-and-beta-cell-dysfunction-to/)
- [International Trial of the Edmonton Protocol for Islet Transplantation](https://scholariq.org/papers/international-trial-of-the-edmonton-protocol-for-islet-transplantation/)

## Topic primary papers

Showing 15 of 169.

- [Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen](https://scholariq.org/papers/islet-transplantation-in-seven-patients-with-type-1-diabetes-mellitus-using-a/)
- [Type 2 diabetes](https://scholariq.org/papers/type-2-diabetes/)
- [The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes](https://scholariq.org/papers/the-relative-contributions-of-insulin-resistance-and-beta-cell-dysfunction-to/)
- [International Trial of the Edmonton Protocol for Islet Transplantation](https://scholariq.org/papers/international-trial-of-the-edmonton-protocol-for-islet-transplantation/)
- [Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)](https://scholariq.org/papers/mutations-in-the-hepatocyte-nuclear-factor-1-gene-in-maturity-onset-diabetes-of/)
- [Quantification of the Relationship Between Insulin Sensitivity and β-Cell Function in Human Subjects: Evidence for a Hyperbolic Function](https://scholariq.org/papers/quantification-of-the-relationship-between-insulin-sensitivity-and-cell-function/)
- [Preservation of Pancreatic β-Cell Function and Prevention of Type 2 Diabetes by Pharmacological Treatment of Insulin Resistance in High-Risk Hispanic Women](https://scholariq.org/papers/preservation-of-pancreatic-cell-function-and-prevention-of-type-2-diabetes-by/)
- [A genome-wide search for human type 1 diabetes susceptibility genes](https://scholariq.org/papers/a-genome-wide-search-for-human-type-1-diabetes-susceptibility-genes/)
- [Fatty acid-induced β cell apoptosis: A link between obesity and diabetes](https://scholariq.org/papers/fatty-acid-induced-cell-apoptosis-a-link-between-obesity-and-diabetes/)
- [A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance](https://scholariq.org/papers/a-genome-wide-approach-accounting-for-body-mass-index-identifies-genetic/)
- [Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol](https://scholariq.org/papers/clinical-outcomes-and-insulin-secretion-after-islet-transplantation-with-the/)
- [Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes](https://scholariq.org/papers/targeted-disruption-of-the-chop-gene-delays-endoplasmic-reticulum-stress/)
- [Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes](https://scholariq.org/papers/multipotential-nestin-positive-stem-cells-isolated-from-adult-pancreatic-islets/)
- [Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (<i>KCNJ11</i>) and SUR1 (<i>ABCC8</i>) Confirm That the <i>KCNJ11</i> E23K Variant Is Associated With Type 2 Diabetes](https://scholariq.org/papers/large-scale-association-studies-of-variants-in-genes-encoding-the-pancreatic/)
- [Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus](https://scholariq.org/papers/susceptibility-to-human-type-1-diabetes-at-iddm2-is-determined-by-tandem-repeat/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.