# Paraoxonase enzyme and polymorphisms

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/paraoxonase-enzyme-and-polymorphisms/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the role of paraoxonase enzymes in atherosclerosis, oxidative stress, and cardiovascular diseases. It explores the genetic polymorphisms, enzyme activity, and the impact of paraoxonase on lipid peroxidation and inflammation. The research also delves into the association between paraoxonase and high-density lipoproteins (HDL) as well as its potential as an antioxidant. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12975 |
| Works | 54 |

## Topic papers all

Showing 15 of 54.

- [Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis](https://scholariq.org/papers/mice-lacking-serum-paraoxonase-are-susceptible-to-organophosphate-toxicity-and/)
- [Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice](https://scholariq.org/papers/pomegranate-juice-consumption-reduces-oxidative-stress-atherogenic-modifications/)
- [Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease](https://scholariq.org/papers/increased-prevalence-of-oxidant-stress-and-inflammation-in-patients-with/)
- [Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans.](https://scholariq.org/papers/absorption-lipoprotein-transport-and-regulation-of-plasma-concentrations-of/)
- [Modulation of paraoxonase (PON1) activity](https://scholariq.org/papers/modulation-of-paraoxonase-pon1-activity/)
- [Apolipoprotein A-I and B Levels and the Risk of Ischemic Heart Disease During a Five-Year Follow-up of Men in the Que´bec Cardiovascular Study](https://scholariq.org/papers/apolipoprotein-a-i-and-b-levels-and-the-risk-of-ischemic-heart-disease-during-a/)
- [Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins](https://scholariq.org/papers/paraoxonase-biochemistry-genetics-and-relationship-to-plasma-lipoproteins/)
- [The Prevalence of Nontraditional Risk Factors for Coronary Heart Disease in Patients with Chronic Kidney Disease](https://scholariq.org/papers/the-prevalence-of-nontraditional-risk-factors-for-coronary-heart-disease-in/)
- [Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood](https://scholariq.org/papers/prenatal-exposure-to-organophosphates-paraoxonase-1-and-cognitive-development-in/)
- [In utero pesticide exposure, maternal paraoxonase activity, and head circumference.](https://scholariq.org/papers/in-utero-pesticide-exposure-maternal-paraoxonase-activity-and-head-circumference/)
- [Pomegranate Juice Supplementation to Atherosclerotic Mice Reduces Macrophage Lipid Peroxidation, Cellular Cholesterol Accumulation and Development of Atherosclerosis](https://scholariq.org/papers/pomegranate-juice-supplementation-to-atherosclerotic-mice-reduces-macrophage/)
- [High-Density Lipoprotein Subpopulation Profile and Coronary Heart Disease Prevalence in Male Participants of the Framingham Offspring Study](https://scholariq.org/papers/high-density-lipoprotein-subpopulation-profile-and-coronary-heart-disease/)
- [Value of High-Density Lipoprotein (HDL) Subpopulations in Predicting Recurrent Cardiovascular Events in the Veterans Affairs HDL Intervention Trial](https://scholariq.org/papers/value-of-high-density-lipoprotein-hdl-subpopulations-in-predicting-recurrent/)
- [Functional Genomics of the Paraoxonase (PON1) Polymorphisms: Effects on Pesticide Sensitivity, Cardiovascular Disease, and Drug Metabolism](https://scholariq.org/papers/functional-genomics-of-the-paraoxonase-pon1-polymorphisms-effects-on-pesticide/)
- [Pomegranate Phenolics from the Peels, Arils, and Flowers Are Antiatherogenic: Studies<i>in Vivo</i>in Atherosclerotic Apolipoprotein E-Deficient (E<sup>0</sup>) Mice and<i>in Vitro</i>in Cultured Macrophages and Lipoproteins](https://scholariq.org/papers/pomegranate-phenolics-from-the-peels-arils-and-flowers-are-antiatherogenic/)

## Topic primary papers

Showing 15 of 20.

- [Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis](https://scholariq.org/papers/mice-lacking-serum-paraoxonase-are-susceptible-to-organophosphate-toxicity-and/)
- [Modulation of paraoxonase (PON1) activity](https://scholariq.org/papers/modulation-of-paraoxonase-pon1-activity/)
- [Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins](https://scholariq.org/papers/paraoxonase-biochemistry-genetics-and-relationship-to-plasma-lipoproteins/)
- [Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood](https://scholariq.org/papers/prenatal-exposure-to-organophosphates-paraoxonase-1-and-cognitive-development-in/)
- [In utero pesticide exposure, maternal paraoxonase activity, and head circumference.](https://scholariq.org/papers/in-utero-pesticide-exposure-maternal-paraoxonase-activity-and-head-circumference/)
- [Functional Genomics of the Paraoxonase (PON1) Polymorphisms: Effects on Pesticide Sensitivity, Cardiovascular Disease, and Drug Metabolism](https://scholariq.org/papers/functional-genomics-of-the-paraoxonase-pon1-polymorphisms-effects-on-pesticide/)
- [Age-related decrease in high-density lipoproteins antioxidant activity is due to an alteration in the PON1's free sulfhydyl groups](https://scholariq.org/papers/age-related-decrease-in-high-density-lipoproteins-antioxidant-activity-is-due-to/)
- [Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection](https://scholariq.org/papers/paraoxonase-2-pon2-in-brain-and-its-potential-role-in-neuroprotection/)
- [Estimation of Oxidative Stress Markers in Chronic Kidney Disease](https://scholariq.org/papers/estimation-of-oxidative-stress-markers-in-chronic-kidney-disease/)
- [Relation between Methylmercury Exposure and Plasma Paraoxonase Activity in Inuit Adults from Nunavik](https://scholariq.org/papers/relation-between-methylmercury-exposure-and-plasma-paraoxonase-activity-in-inuit/)
- [Modulation of Paraoxonase 2 (PON2) in Mouse Brain by the Polyphenol Quercetin: A Mechanism of Neuroprotection?](https://scholariq.org/papers/modulation-of-paraoxonase-2-pon2-in-mouse-brain-by-the-polyphenol-quercetin-a/)
- [Comparative effects of pioglitazone and metformin on oxidative stress markers in newly diagnosed type 2 diabetes patients: A randomized clinical trial](https://scholariq.org/papers/comparative-effects-of-pioglitazone-and-metformin-on-oxidative-stress-markers-in/)
- [Relationship between human paraoxonase-1 activity and PON1 polymorphisms in Mexican workers exposed to organophosphate pesticides](https://scholariq.org/papers/relationship-between-human-paraoxonase-1-activity-and-pon1-polymorphisms-in/)
- [Interaction between organophosphate pesticide exposure and PON1 activity on thyroid function](https://scholariq.org/papers/interaction-between-organophosphate-pesticide-exposure-and-pon1-activity-on/)
- [Association of serum paraoxonase enzyme activity and oxidative stress markers with dyslipidemia in obese adolescents](https://scholariq.org/papers/association-of-serum-paraoxonase-enzyme-activity-and-oxidative-stress-markers/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.