# Parkinson's Disease Mechanisms and Treatments

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/parkinson-s-disease-mechanisms-and-treatments-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 3,684,157 |
| Description | This cluster of papers explores the pathophysiology, clinical features, diagnosis, genetic risk factors, and management of Parkinson's disease. It delves into the role of a-synuclein, neurodegeneration, dopaminergic neurons, oxidative stress, and mitochondrial dysfunction in the development and progression of the disease. Additionally, it discusses the non-motor symptoms and Lewy body pathology associated with Parkinson's disease. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | https://openalex.org/T10085 |
| Works | 128,817 |

## Topic researchers

Showing 12 of 20.

- [Christopher J L Murray](https://scholariq.org/researchers/christopher-j-l-murray/)
- [Rob Knight](https://scholariq.org/researchers/rob-knight/)
- [Simon I Hay](https://scholariq.org/researchers/simon-i-hay/)
- [George Davey Smith](https://scholariq.org/researchers/george-davey-smith/)
- [Theo Vos](https://scholariq.org/researchers/theo-vos/)
- [Walter C. Willett](https://scholariq.org/researchers/walter-c-willett/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Peer Bork](https://scholariq.org/researchers/peer-bork/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [Jun Wang](https://scholariq.org/researchers/jun-wang-11/)
- [Valery L. Feigin](https://scholariq.org/researchers/valery-l-feigin/)
- [John P. A. Ioannidis](https://scholariq.org/researchers/john-p-a-ioannidis/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
