# Phagocytosis and Immune Regulation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/phagocytosis-and-immune-regulation/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the mechanisms and regulation of apoptotic cell clearance, including the role of CD47, phagocytosis, TAM receptors, efferocytosis, and the implications for cancer immunotherapy. It explores the involvement of various molecules and pathways in the recognition and removal of apoptotic cells by phagocytes, shedding light on potential therapeutic targets for immune-related diseases. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t12672 |
| Works | 151 |

## Topic papers all

Showing 15 of 151.

- [Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis](https://scholariq.org/papers/requirement-for-ceramide-initiated-sapk-jnk-signalling-in-stress-induced/)
- [CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells](https://scholariq.org/papers/cd47-is-an-adverse-prognostic-factor-and-therapeutic-antibody-target-on-human/)
- [The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors](https://scholariq.org/papers/the-cd47-signal-regulatory-protein-alpha-sirpa-interaction-is-a-therapeutic/)
- [JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy](https://scholariq.org/papers/jnk1-mediated-phosphorylation-of-bcl-2-regulates-starvation-induced-autophagy/)
- [Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer](https://scholariq.org/papers/activation-of-the-axl-kinase-causes-resistance-to-egfr-targeted-therapy-in-lung/)
- [An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance](https://scholariq.org/papers/an-epithelial-mesenchymal-transition-gene-signature-predicts-resistance-to-egfr/)
- [Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis](https://scholariq.org/papers/pannexin-1-channels-mediate-find-me-signal-release-and-membrane-permeability/)
- [Targeting tumor-associated macrophages to synergize tumor immunotherapy](https://scholariq.org/papers/targeting-tumor-associated-macrophages-to-synergize-tumor-immunotherapy/)
- [A conserved dendritic-cell regulatory program limits antitumour immunity](https://scholariq.org/papers/a-conserved-dendritic-cell-regulatory-program-limits-antitumour-immunity/)
- [Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses](https://scholariq.org/papers/targeting-tumor-infiltrating-macrophages-decreases-tumor-initiating-cells/)
- [Renal tubule injury: a driving force toward chronic kidney disease](https://scholariq.org/papers/renal-tubule-injury-a-driving-force-toward-chronic-kidney-disease/)
- [Integrin-associated protein (CD47) and its ligands](https://scholariq.org/papers/integrin-associated-protein-cd47-and-its-ligands/)
- [Regulated cell death (RCD) in cancer: key pathways and targeted therapies](https://scholariq.org/papers/regulated-cell-death-rcd-in-cancer-key-pathways-and-targeted-therapies/)
- [Decreased Resistance to Bacterial Infection and Granulocyte Defects in IAP-Deficient Mice](https://scholariq.org/papers/decreased-resistance-to-bacterial-infection-and-granulocyte-defects-in-iap/)
- [CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration](https://scholariq.org/papers/ced-12-elmo-a-novel-member-of-the-crkii-dock180-rac-pathway-is-required-for/)

## Topic primary papers

Showing 15 of 57.

- [CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells](https://scholariq.org/papers/cd47-is-an-adverse-prognostic-factor-and-therapeutic-antibody-target-on-human/)
- [The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors](https://scholariq.org/papers/the-cd47-signal-regulatory-protein-alpha-sirpa-interaction-is-a-therapeutic/)
- [An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance](https://scholariq.org/papers/an-epithelial-mesenchymal-transition-gene-signature-predicts-resistance-to-egfr/)
- [Renal tubule injury: a driving force toward chronic kidney disease](https://scholariq.org/papers/renal-tubule-injury-a-driving-force-toward-chronic-kidney-disease/)
- [Integrin-associated protein (CD47) and its ligands](https://scholariq.org/papers/integrin-associated-protein-cd47-and-its-ligands/)
- [Decreased Resistance to Bacterial Infection and Granulocyte Defects in IAP-Deficient Mice](https://scholariq.org/papers/decreased-resistance-to-bacterial-infection-and-granulocyte-defects-in-iap/)
- [CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration](https://scholariq.org/papers/ced-12-elmo-a-novel-member-of-the-crkii-dock180-rac-pathway-is-required-for/)
- [Phagosome maturation: going through the acid test](https://scholariq.org/papers/phagosome-maturation-going-through-the-acid-test/)
- [Systemic Lupus Erythematosus, Complement Deficiency, and Apoptosis](https://scholariq.org/papers/systemic-lupus-erythematosus-complement-deficiency-and-apoptosis/)
- [Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL](https://scholariq.org/papers/novel-mechanism-of-lapatinib-resistance-in-her2-positive-breast-tumor-cells/)
- [Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair](https://scholariq.org/papers/efferocytosis-fuels-requirements-of-fatty-acid-oxidation-and-the-electron/)
- [Burying the Dead](https://scholariq.org/papers/burying-the-dead/)
- [Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses](https://scholariq.org/papers/tumor-innate-immunity-primed-by-specific-interferon-stimulated-endogenous/)
- [Inhibition of T–Cell Responses by Hepatic Stellate Cells Via B7–H1-Mediated T–Cell Apoptosis in Mice](https://scholariq.org/papers/inhibition-of-t-cell-responses-by-hepatic-stellate-cells-via-b7-h1-mediated-t/)
- [Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion](https://scholariq.org/papers/phosphatidylserine-receptor-bai1-and-apoptotic-cells-as-new-promoters-of/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.