# Phosphodiesterase function and regulation

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/phosphodiesterase-function-and-regulation-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 445,923 |
| Description | This cluster of papers focuses on the molecular regulation and clinical applications of cyclic nucleotide phosphodiesterases (PDEs), particularly in the context of cAMP signaling, schizophrenia genetics, neuronal development, therapeutic targeting, compartmentalized signaling, Alzheimer's disease treatment, cardiac function regulation, and the development of phosphodiesterase inhibitors. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T12434 |
| Works | 22,821 |

## Topic researchers

Showing 12 of 20.

- [David Moher](https://scholariq.org/researchers/david-moher/)
- [John Q. Trojanowski](https://scholariq.org/researchers/john-q-trojanowski/)
- [John Hardy](https://scholariq.org/researchers/john-hardy/)
- [Eric Boerwinkle](https://scholariq.org/researchers/eric-boerwinkle/)
- [Peter J. Barnes](https://scholariq.org/researchers/peter-j-barnes/)
- [Kāri Stefánsson](https://scholariq.org/researchers/kari-stefansson/)
- [John J. McGrath](https://scholariq.org/researchers/john-j-mcgrath/)
- [Paul M. Thompson](https://scholariq.org/researchers/paul-m-thompson/)
- [Rafael Tabarés‐Seisdedos](https://scholariq.org/researchers/rafael-tabares-seisdedos/)
- [Vilmundur Guðnason](https://scholariq.org/researchers/vilmundur-gu-nason/)
- [Jaakko Kaprio](https://scholariq.org/researchers/jaakko-kaprio/)
- [Solomon H. Snyder](https://scholariq.org/researchers/solomon-h-snyder/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.