# Plant-derived Lignans Synthesis and Bioactivity

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/plant-derived-lignans-synthesis-and-bioactivity/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the biosynthesis, pharmacological activities, and medicinal applications of lignans, including compounds such as podophyllotoxin, schisandrin, arctigenin, and related derivatives. It covers research on various plant sources, enzymatic pathways, cytotoxicity, anti-inflammatory effects, and potential therapeutic uses of lignans in cancer treatment, neuroprotection, hepatoprotection, and antimicrobial activities. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12360 |
| Works | 16 |

## Topic papers all

Showing 15 of 16.

- [Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation](https://scholariq.org/papers/arctigenin-a-dietary-phytoestrogen-induces-apoptosis-of-estrogen-receptor/)
- [Effect and mechanism of senkyunolide I as an anti-migraine compound from <i>Ligusticum chuanxiong</i>](https://scholariq.org/papers/effect-and-mechanism-of-senkyunolide-i-as-an-anti-migraine-compound-from-i/)
- [The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth](https://scholariq.org/papers/the-flaxseed-lignan-secoisolariciresinol-diglucoside-decreases-local/)
- [Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine](https://scholariq.org/papers/therapeutic-potential-of-bicyclol-in-liver-diseases-lessons-from-a-synthetic/)
- [Schisandrin B Prevents Doxorubicin-Induced Chronic Cardiotoxicity and Enhances Its Anticancer Activity In Vivo](https://scholariq.org/papers/schisandrin-b-prevents-doxorubicin-induced-chronic-cardiotoxicity-and-enhances/)
- [Intake of the plant lignans matairesinol, secoisolariciresinol, pinoresinol, and lariciresinol in relation to vascular inflammation and endothelial dysfunction in middle age-elderly men and post-menopausal women living in Northern Italy](https://scholariq.org/papers/intake-of-the-plant-lignans-matairesinol-secoisolariciresinol-pinoresinol-and/)
- [Protective effects on myocardial infarction model: delivery of schisandrin B using matrix metalloproteinase-sensitive peptide-modified, PEGylated lipid nanoparticles](https://scholariq.org/papers/protective-effects-on-myocardial-infarction-model-delivery-of-schisandrin-b/)
- [RETRACTED: Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells](https://scholariq.org/papers/retracted-schisandrin-b-induces-apoptosis-and-cell-cycle-arrest-of-gallbladder/)
- [Chemistry and Pharmacological Activity of Sesquiterpenoids from the Chrysanthemum Genus](https://scholariq.org/papers/chemistry-and-pharmacological-activity-of-sesquiterpenoids-from-the/)
- [Neuroprotective Potency of Neolignans in Magnolia officinalis Cortex Against Brain Disorders](https://scholariq.org/papers/neuroprotective-potency-of-neolignans-in-magnolia-officinalis-cortex-against/)
- [ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model](https://scholariq.org/papers/ono-8430506-a-novel-autotaxin-inhibitor-that-enhances-the-antitumor-effect-of/)
- [Cathodic reductive coupling of methyl cinnamate on boron-doped diamond electrodes and synthesis of new neolignan-type products](https://scholariq.org/papers/cathodic-reductive-coupling-of-methyl-cinnamate-on-boron-doped-diamond/)
- [Assessment of nutritional and medicinal properties of nutmeg](https://scholariq.org/papers/assessment-of-nutritional-and-medicinal-properties-of-nutmeg/)
- [Blocking effects of heteroclitin D and gomisin J on L-type calcium channels in ventricular cells of guinea pig.](https://scholariq.org/papers/blocking-effects-of-heteroclitin-d-and-gomisin-j-on-l-type-calcium-channels-in/)
- [Anti-invasion and anti-metastasis effects of Valjatrate E via reduction of matrix metalloproteinases expression and suppression of MAPK/ERK signaling pathway](https://scholariq.org/papers/anti-invasion-and-anti-metastasis-effects-of-valjatrate-e-via-reduction-of/)

## Topic primary papers

- [Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine](https://scholariq.org/papers/therapeutic-potential-of-bicyclol-in-liver-diseases-lessons-from-a-synthetic/)
- [Schisandrin B Prevents Doxorubicin-Induced Chronic Cardiotoxicity and Enhances Its Anticancer Activity In Vivo](https://scholariq.org/papers/schisandrin-b-prevents-doxorubicin-induced-chronic-cardiotoxicity-and-enhances/)
- [Protective effects on myocardial infarction model: delivery of schisandrin B using matrix metalloproteinase-sensitive peptide-modified, PEGylated lipid nanoparticles](https://scholariq.org/papers/protective-effects-on-myocardial-infarction-model-delivery-of-schisandrin-b/)
- [RETRACTED: Schisandrin B Induces Apoptosis and Cell Cycle Arrest of Gallbladder Cancer Cells](https://scholariq.org/papers/retracted-schisandrin-b-induces-apoptosis-and-cell-cycle-arrest-of-gallbladder/)
- [Cathodic reductive coupling of methyl cinnamate on boron-doped diamond electrodes and synthesis of new neolignan-type products](https://scholariq.org/papers/cathodic-reductive-coupling-of-methyl-cinnamate-on-boron-doped-diamond/)
- [Assessment of nutritional and medicinal properties of nutmeg](https://scholariq.org/papers/assessment-of-nutritional-and-medicinal-properties-of-nutmeg/)
- [Blocking effects of heteroclitin D and gomisin J on L-type calcium channels in ventricular cells of guinea pig.](https://scholariq.org/papers/blocking-effects-of-heteroclitin-d-and-gomisin-j-on-l-type-calcium-channels-in/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.