# Porphyrin Metabolism and Disorders

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/porphyrin-metabolism-and-disorders-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 658,037 |
| Description | This cluster of papers explores the molecular mechanisms of heme biosynthesis, including the catalysis by cobalamin-dependent enzymes, genetic mutations leading to porphyrias, microbial production of vitamin B12, and the use of RNA interference therapy and liver transplantation for the treatment of related disorders. It also delves into metabolic engineering and genomic analysis related to heme biosynthesis pathways. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T12441 |
| Works | 49,650 |

## Topic researchers

Showing 12 of 20.

- [Steven L. Salzberg](https://scholariq.org/researchers/steven-l-salzberg/)
- [John Hardy](https://scholariq.org/researchers/john-hardy/)
- [Tom Maniatis](https://scholariq.org/researchers/tom-maniatis/)
- [George M. Sheldrick](https://scholariq.org/researchers/george-m-sheldrick/)
- [Bruce M. Spiegelman](https://scholariq.org/researchers/bruce-m-spiegelman/)
- [Barry Halliwell](https://scholariq.org/researchers/barry-halliwell/)
- [Martin Karplus](https://scholariq.org/researchers/martin-karplus/)
- [George M. Church](https://scholariq.org/researchers/george-m-church/)
- [R Myers](https://scholariq.org/researchers/r-myers/)
- [Thomas Meitinger](https://scholariq.org/researchers/thomas-meitinger/)
- [John C. Reed](https://scholariq.org/researchers/john-c-reed/)
- [L. Adrienne Cupples](https://scholariq.org/researchers/l-adrienne-cupples/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.