# Psychedelics and Drug Studies

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/psychedelics-and-drug-studies/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the therapeutic potential of psychedelic therapy, particularly focusing on the use of substances like psilocybin and MDMA for the treatment of depression, anxiety, and substance dependence. The research delves into the neurobiology, serotonin receptors, and brain function underlying the effects of these psychedelics, as well as their ability to induce mystical experiences and promote long-lasting positive changes in psychological functioning. |
| Domain | Social Sciences |
| Field | Psychology |
| OpenAlex ID | t12553 |
| Works | 100 |

## Topic papers all

Showing 15 of 100.

- [Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review](https://scholariq.org/papers/cannabis-use-and-risk-of-psychotic-or-affective-mental-health-outcomes-a/)
- [Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial](https://scholariq.org/papers/psilocybin-produces-substantial-and-sustained-decreases-in-depression-and/)
- [Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin](https://scholariq.org/papers/neural-correlates-of-the-psychedelic-state-as-determined-by-fmri-studies-with/)
- [Causal association between cannabis and psychosis: examination of the evidence](https://scholariq.org/papers/causal-association-between-cannabis-and-psychosis-examination-of-the-evidence/)
- [Neural correlates of the LSD experience revealed by multimodal neuroimaging](https://scholariq.org/papers/neural-correlates-of-the-lsd-experience-revealed-by-multimodal-neuroimaging/)
- [Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study](https://scholariq.org/papers/efficacy-and-safety-of-flexibly-dosed-esketamine-nasal-spray-combined-with-a/)
- [Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial](https://scholariq.org/papers/rapid-antidepressant-effects-of-the-psychedelic-ayahuasca-in-treatment-resistant/)
- [Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression](https://scholariq.org/papers/efficacy-of-esketamine-nasal-spray-plus-oral-antidepressant-treatment-for/)
- [History of cannabis as a medicine: a review](https://scholariq.org/papers/history-of-cannabis-as-a-medicine-a-review/)
- [Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study](https://scholariq.org/papers/efficacy-and-safety-of-intranasal-esketamine-for-the-rapid-reduction-of-symptoms/)
- [Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1)](https://scholariq.org/papers/efficacy-and-safety-of-fixed-dose-esketamine-nasal-spray-combined-with-a-new/)
- [Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials](https://scholariq.org/papers/lysergic-acid-diethylamide-lsd-for-alcoholism-meta-analysis-of-randomized/)
- [Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis](https://scholariq.org/papers/cannabinoids-for-the-treatment-of-mental-disorders-and-symptoms-of-mental/)
- [Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent](https://scholariq.org/papers/safety-and-side-effects-of-cannabidiol-a-cannabis-sativa-constituent/)
- [Cannabis and anxiety: a critical review of the evidence](https://scholariq.org/papers/cannabis-and-anxiety-a-critical-review-of-the-evidence/)

## Topic primary papers

Showing 15 of 24.

- [Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial](https://scholariq.org/papers/psilocybin-produces-substantial-and-sustained-decreases-in-depression-and/)
- [Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin](https://scholariq.org/papers/neural-correlates-of-the-psychedelic-state-as-determined-by-fmri-studies-with/)
- [Neural correlates of the LSD experience revealed by multimodal neuroimaging](https://scholariq.org/papers/neural-correlates-of-the-lsd-experience-revealed-by-multimodal-neuroimaging/)
- [Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial](https://scholariq.org/papers/rapid-antidepressant-effects-of-the-psychedelic-ayahuasca-in-treatment-resistant/)
- [Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials](https://scholariq.org/papers/lysergic-acid-diethylamide-lsd-for-alcoholism-meta-analysis-of-randomized/)
- [Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report](https://scholariq.org/papers/antidepressant-effects-of-a-single-dose-of-ayahuasca-in-patients-with-recurrent/)
- [Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression](https://scholariq.org/papers/antidepressant-effects-of-a-single-dose-of-ayahuasca-in-patients-with-recurrent-2/)
- [Psychedelics and Mental Health: A Population Study](https://scholariq.org/papers/psychedelics-and-mental-health-a-population-study/)
- [Psychedelics not linked to mental health problems or suicidal behavior: A population study](https://scholariq.org/papers/psychedelics-not-linked-to-mental-health-problems-or-suicidal-behavior-a/)
- [Default Mode Network Modulation by Psychedelics: A Systematic Review](https://scholariq.org/papers/default-mode-network-modulation-by-psychedelics-a-systematic-review/)
- [Over 30 million psychedelic users in the United States](https://scholariq.org/papers/over-30-million-psychedelic-users-in-the-united-states/)
- [The non-hallucinogen 2-bromo-lysergic acid diethylamide as preventative treatment for cluster headache: An open, non-randomized case series](https://scholariq.org/papers/the-non-hallucinogen-2-bromo-lysergic-acid-diethylamide-as-preventative/)
- [Ayahuasca use and reported effects on depression and anxiety symptoms: An international cross-sectional study of 11,912 consumers](https://scholariq.org/papers/ayahuasca-use-and-reported-effects-on-depression-and-anxiety-symptoms-an/)
- [A systematic literature review of clinical trials and therapeutic applications of ibogaine](https://scholariq.org/papers/a-systematic-literature-review-of-clinical-trials-and-therapeutic-applications/)
- [Medicinal psychedelics for mental health and addiction: Advancing research of an emerging paradigm](https://scholariq.org/papers/medicinal-psychedelics-for-mental-health-and-addiction-advancing-research-of-an/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.