# Receptor Mechanisms and Signaling

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/receptor-mechanisms-and-signaling/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the structure, function, and signaling mechanisms of G protein-coupled receptors (GPCRs), with a focus on crystal structures, signal transduction, arrestin-mediated pathways, pharmacology, drug discovery, receptor activation, biased signaling, and the molecular mechanisms involved. The research covers a wide range of topics related to GPCRs and their implications in various biological processes. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11178 |
| Works | 308 |

## Topic papers all

Showing 15 of 308.

- [A novel potent vasoconstrictor peptide produced by vascular endothelial cells](https://scholariq.org/papers/a-novel-potent-vasoconstrictor-peptide-produced-by-vascular-endothelial-cells/)
- [Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region](https://scholariq.org/papers/association-of-anxiety-related-traits-with-a-polymorphism-in-the-serotonin/)
- [Angiotensin-converting enzyme 2 protects from severe acute lung failure](https://scholariq.org/papers/angiotensin-converting-enzyme-2-protects-from-severe-acute-lung-failure/)
- [Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor](https://scholariq.org/papers/cloning-of-a-cdna-encoding-a-non-isopeptide-selective-subtype-of-the-endothelin/)
- [Serotonin Transporter Genetic Variation and the Response of the Human Amygdala](https://scholariq.org/papers/serotonin-transporter-genetic-variation-and-the-response-of-the-human-amygdala/)
- [Allelic Variation of Human Serotonin Transporter Gene Expression](https://scholariq.org/papers/allelic-variation-of-human-serotonin-transporter-gene-expression/)
- [Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine](https://scholariq.org/papers/acetylcholine-receptors-containing-the-2-subunit-are-involved-in-the-reinforcing/)
- [Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.](https://scholariq.org/papers/beta-1-and-beta-2-adrenergic-receptor-subpopulations-in-nonfailing-and-failing/)
- [Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning](https://scholariq.org/papers/phasic-firing-in-dopaminergic-neurons-is-sufficient-for-behavioral-conditioning/)
- [Nucleus Accumbens D2/3 Receptors Predict Trait Impulsivity and Cocaine Reinforcement](https://scholariq.org/papers/nucleus-accumbens-d2-3-receptors-predict-trait-impulsivity-and-cocaine/)
- [How can drug addiction help us understand obesity?](https://scholariq.org/papers/how-can-drug-addiction-help-us-understand-obesity/)
- [Neurobiology of addiction](https://scholariq.org/papers/neurobiology-of-addiction/)
- [Neuroleptics and operant behavior: The anhedonia hypothesis](https://scholariq.org/papers/neuroleptics-and-operant-behavior-the-anhedonia-hypothesis/)
- [An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3](https://scholariq.org/papers/an-endocytic-pathway-essential-for-renal-uptake-and-activation-of-the-steroid-25/)
- [Incubation of cocaine craving after withdrawal](https://scholariq.org/papers/incubation-of-cocaine-craving-after-withdrawal/)

## Topic primary papers

Showing 15 of 68.

- [Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region](https://scholariq.org/papers/association-of-anxiety-related-traits-with-a-polymorphism-in-the-serotonin/)
- [Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning](https://scholariq.org/papers/phasic-firing-in-dopaminergic-neurons-is-sufficient-for-behavioral-conditioning/)
- [A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation](https://scholariq.org/papers/a-peptide-derived-from-a-2-adrenergic-receptor-transmembrane-domain-inhibits/)
- [Intranasal insulin improves memory in humans](https://scholariq.org/papers/intranasal-insulin-improves-memory-in-humans/)
- [Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II](https://scholariq.org/papers/mechanical-stress-activates-angiotensin-ii-type-1-receptor-without-the/)
- [Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human](https://scholariq.org/papers/dysfunction-of-lipid-sensor-gpr120-leads-to-obesity-in-both-mouse-and-human/)
- [α<sub>1</sub>-Adrenergic Receptor Subtypes](https://scholariq.org/papers/sub-1-sub-adrenergic-receptor-subtypes/)
- [Megalin Knockout Mice as an Animal Model of Low Molecular Weight Proteinuria](https://scholariq.org/papers/megalin-knockout-mice-as-an-animal-model-of-low-molecular-weight-proteinuria/)
- [Yohimbine: a pharmacological probe for study of the alpha 2-adrenoreceptor.](https://scholariq.org/papers/yohimbine-a-pharmacological-probe-for-study-of-the-alpha-2-adrenoreceptor/)
- [Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography](https://scholariq.org/papers/structure-of-the-angiotensin-receptor-revealed-by-serial-femtosecond/)
- [Solution-phase library screening for the identification of rare clones: isolation of an alpha 1D-adrenergic receptor cDNA.](https://scholariq.org/papers/solution-phase-library-screening-for-the-identification-of-rare-clones-isolation/)
- [Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain](https://scholariq.org/papers/characterization-and-development-of-angiotensin-ii-receptor-subtypes-at1-and-at2/)
- [Design, Synthesis, and Biological Evaluation of the First Selective Nonpeptide AT<sub>2</sub> Receptor Agonist](https://scholariq.org/papers/design-synthesis-and-biological-evaluation-of-the-first-selective-nonpeptide-at/)
- [Pavlovian Conditioning of Rat Mucosal Mast Cells to Secrete Rat Mast Cell Protease II](https://scholariq.org/papers/pavlovian-conditioning-of-rat-mucosal-mast-cells-to-secrete-rat-mast-cell/)
- [mu-Opioid receptor knockout mice do not self-administer alcohol.](https://scholariq.org/papers/mu-opioid-receptor-knockout-mice-do-not-self-administer-alcohol/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.