# Regulation of Appetite and Obesity

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/regulation-of-appetite-and-obesity/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the neuroendocrine regulation of appetite and body weight, focusing on the roles of leptin, ghrelin, and insulin in modulating food intake and energy balance. It delves into the intricate neural circuits within the hypothalamus and their interactions with various hormonal signals to regulate feeding behavior and metabolic homeostasis. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t10489 |
| Works | 367 |

## Topic papers all

Showing 15 of 367.

- [Increased oxidative stress in obesity and its impact on metabolic syndrome](https://scholariq.org/papers/increased-oxidative-stress-in-obesity-and-its-impact-on-metabolic-syndrome/)
- [The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity](https://scholariq.org/papers/the-fat-derived-hormone-adiponectin-reverses-insulin-resistance-associated-with/)
- [The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity](https://scholariq.org/papers/the-hypocretins-hypothalamus-specific-peptides-with-neuroexcitatory-activity/)
- [Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects](https://scholariq.org/papers/leptin-levels-in-human-and-rodent-measurement-of-plasma-leptin-and-ob-rna-in/)
- [Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems](https://scholariq.org/papers/neurons-containing-hypocretin-orexin-project-to-multiple-neuronal-systems/)
- [Narcolepsy in orexin Knockout Mice](https://scholariq.org/papers/narcolepsy-in-orexin-knockout-mice/)
- [Differential Significance of Plasma Visfatin Concentrations according to Adiposity in Children and Adolescents](https://scholariq.org/papers/differential-significance-of-plasma-visfatin-concentrations-according-to/)
- [Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index](https://scholariq.org/papers/association-analyses-of-249-796-individuals-reveal-18-new-loci-associated-with/)
- [The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene](https://scholariq.org/papers/the-sleep-disorder-canine-narcolepsy-is-caused-by-a-mutation-in-the-hypocretin/)
- [Adiponectin and Adiponectin Receptors](https://scholariq.org/papers/adiponectin-and-adiponectin-receptors/)
- [Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index](https://scholariq.org/papers/short-sleep-duration-is-associated-with-reduced-leptin-elevated-ghrelin-and/)
- [Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity.](https://scholariq.org/papers/homeostasis-model-assessment-closely-mirrors-the-glucose-clamp-technique-in-the/)
- [A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains](https://scholariq.org/papers/a-mutation-in-a-case-of-early-onset-narcolepsy-and-a-generalized-absence-of/)
- [A role for glucagon-like peptide-1 in the central regulation of feeding](https://scholariq.org/papers/a-role-for-glucagon-like-peptide-1-in-the-central-regulation-of-feeding/)
- [Hypocretin (orexin) deficiency in human narcolepsy](https://scholariq.org/papers/hypocretin-orexin-deficiency-in-human-narcolepsy/)

## Topic primary papers

Showing 15 of 120.

- [The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity](https://scholariq.org/papers/the-hypocretins-hypothalamus-specific-peptides-with-neuroexcitatory-activity/)
- [Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects](https://scholariq.org/papers/leptin-levels-in-human-and-rodent-measurement-of-plasma-leptin-and-ob-rna-in/)
- [Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index](https://scholariq.org/papers/association-analyses-of-249-796-individuals-reveal-18-new-loci-associated-with/)
- [A role for glucagon-like peptide-1 in the central regulation of feeding](https://scholariq.org/papers/a-role-for-glucagon-like-peptide-1-in-the-central-regulation-of-feeding/)
- [Leptin Regulates Bone Formation via the Sympathetic Nervous System](https://scholariq.org/papers/leptin-regulates-bone-formation-via-the-sympathetic-nervous-system/)
- [Leptin regulation of bone resorption by the sympathetic nervous system and CART](https://scholariq.org/papers/leptin-regulation-of-bone-resorption-by-the-sympathetic-nervous-system-and-cart/)
- [Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans](https://scholariq.org/papers/stomach-is-a-major-source-of-circulating-ghrelin-and-feeding-state-determines/)
- [The stomach is a source of leptin](https://scholariq.org/papers/the-stomach-is-a-source-of-leptin/)
- [Biological, Physiological, Pathophysiological, and Pharmacological Aspects of Ghrelin](https://scholariq.org/papers/biological-physiological-pathophysiological-and-pharmacological-aspects-of/)
- [Ghrelin](https://scholariq.org/papers/ghrelin/)
- [Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite](https://scholariq.org/papers/ghrelin-modulates-the-activity-and-synaptic-input-organization-of-midbrain/)
- [Ghrelin Strongly Stimulates Growth Hormone Release in Humans](https://scholariq.org/papers/ghrelin-strongly-stimulates-growth-hormone-release-in-humans/)
- [Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake](https://scholariq.org/papers/adiponectin-stimulates-amp-activated-protein-kinase-in-the-hypothalamus-and/)
- [Central obesity and increased risk of dementia more than three decades later](https://scholariq.org/papers/central-obesity-and-increased-risk-of-dementia-more-than-three-decades-later/)
- [Corticotropin Releasing Hormone and Proopiomelanocortin Involvement in the Cutaneous Response to Stress](https://scholariq.org/papers/corticotropin-releasing-hormone-and-proopiomelanocortin-involvement-in-the/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.