# Retinal Development and Disorders

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/retinal-development-and-disorders/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the molecular mechanisms underlying retinal degeneration, including diseases such as retinitis pigmentosa and macular degeneration. It also explores potential therapeutic approaches such as gene therapy and the use of retinal stem cells for regeneration. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10691 |
| Works | 200 |

## Topic papers all

Showing 15 of 200.

- [Borders of Multiple Visual Areas in Humans Revealed by Functional Magnetic Resonance Imaging](https://scholariq.org/papers/borders-of-multiple-visual-areas-in-humans-revealed-by-functional-magnetic/)
- [Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial](https://scholariq.org/papers/efficacy-and-safety-of-voretigene-neparvovec-aav2-hrpe65v2-in-patients-with/)
- [Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP](https://scholariq.org/papers/inhibition-of-postsynaptic-pkc-or-camkii-blocks-induction-but-not-expression-of/)
- [Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies](https://scholariq.org/papers/age-related-macular-degeneration-etiology-pathogenesis-and-therapeutic/)
- [Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos](https://scholariq.org/papers/cytosine-base-editor-generates-substantial-off-target-single-nucleotide-variants/)
- [Seven new loci associated with age-related macular degeneration](https://scholariq.org/papers/seven-new-loci-associated-with-age-related-macular-degeneration/)
- [Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis](https://scholariq.org/papers/long-term-effect-of-gene-therapy-on-leber-s-congenital-amaurosis/)
- [Primary open-angle glaucoma](https://scholariq.org/papers/primary-open-angle-glaucoma/)
- [Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes](https://scholariq.org/papers/single-cell-profiles-of-retinal-ganglion-cells-differing-in-resilience-to-injury/)
- [A Phase II Randomized Double-Masked Trial of Pegaptanib, an Anti–Vascular Endothelial Growth Factor Aptamer, for Diabetic Macular Edema](https://scholariq.org/papers/a-phase-ii-randomized-double-masked-trial-of-pegaptanib-an-anti-vascular/)
- [Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research](https://scholariq.org/papers/effects-of-all-trans-retinoic-acid-on-human-sh-sy5y-neuroblastoma-as-in-vitro/)
- [Mutations in SOX2 cause anophthalmia](https://scholariq.org/papers/mutations-in-sox2-cause-anophthalmia/)
- [Glaucoma: now and beyond](https://scholariq.org/papers/glaucoma-now-and-beyond/)
- [Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration](https://scholariq.org/papers/complement-c3-inhibitor-pegcetacoplan-for-geographic-atrophy-secondary-to-age/)
- [Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries](https://scholariq.org/papers/genome-wide-meta-analysis-identifies-127-open-angle-glaucoma-loci-with/)

## Topic primary papers

Showing 15 of 82.

- [Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial](https://scholariq.org/papers/efficacy-and-safety-of-voretigene-neparvovec-aav2-hrpe65v2-in-patients-with/)
- [Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis](https://scholariq.org/papers/long-term-effect-of-gene-therapy-on-leber-s-congenital-amaurosis/)
- [Parasol and midget ganglion cells of the human retina](https://scholariq.org/papers/parasol-and-midget-ganglion-cells-of-the-human-retina/)
- [In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse](https://scholariq.org/papers/in-frame-deletion-in-a-novel-centrosomal-ciliary-protein-cep290-nphp6-perturbs/)
- [Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa.](https://scholariq.org/papers/morphometric-analysis-of-the-extramacular-retina-from-postmortem-eyes-with/)
- [Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options](https://scholariq.org/papers/stargardt-disease-clinical-features-molecular-genetics-animal-models-and/)
- [Retinal Neurogenesis: The Formation of the Initial Central Patch of Postmitotic Cells](https://scholariq.org/papers/retinal-neurogenesis-the-formation-of-the-initial-central-patch-of-postmitotic/)
- [Gene therapy for red–green colour blindness in adult primates](https://scholariq.org/papers/gene-therapy-for-red-green-colour-blindness-in-adult-primates/)
- [Leber congenital amaurosis/early-onset severe retinal dystrophy: clinical features, molecular genetics and therapeutic interventions](https://scholariq.org/papers/leber-congenital-amaurosis-early-onset-severe-retinal-dystrophy-clinical/)
- [The mechanism of cone cell death in Retinitis Pigmentosa](https://scholariq.org/papers/the-mechanism-of-cone-cell-death-in-retinitis-pigmentosa/)
- [The cone dysfunction syndromes: Table 1](https://scholariq.org/papers/the-cone-dysfunction-syndromes-table-1/)
- [Retinal Dopamine Mediates Multiple Dimensions of Light-Adapted Vision](https://scholariq.org/papers/retinal-dopamine-mediates-multiple-dimensions-of-light-adapted-vision/)
- [Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina](https://scholariq.org/papers/novel-properties-of-tyrosine-mutant-aav2-vectors-in-the-mouse-retina/)
- [Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients](https://scholariq.org/papers/gene-correction-reverses-ciliopathy-and-photoreceptor-loss-in-ipsc-derived/)
- [In Vivo Two-Photon Imaging Reveals a Role of Arc in Enhancing Orientation Specificity in Visual Cortex](https://scholariq.org/papers/in-vivo-two-photon-imaging-reveals-a-role-of-arc-in-enhancing-orientation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.