# RNA Interference and Gene Delivery

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/rna-interference-and-gene-delivery/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t10725 |
| Works | 320 |

## Topic papers all

Showing 15 of 320.

- [Molecular characterization of mitochondrial apoptosis-inducing factor](https://scholariq.org/papers/molecular-characterization-of-mitochondrial-apoptosis-inducing-factor/)
- [A global double‐fluorescent Cre reporter mouse](https://scholariq.org/papers/a-global-double-fluorescent-cre-reporter-mouse/)
- [Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy-4th/)
- [Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response](https://scholariq.org/papers/successful-transduction-of-liver-in-hemophilia-by-aav-factor-ix-and-limitations/)
- [Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma](https://scholariq.org/papers/immunologic-and-therapeutic-evaluation-of-a-synthetic-peptide-vaccine-for-the/)
- [CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells](https://scholariq.org/papers/cd47-is-an-adverse-prognostic-factor-and-therapeutic-antibody-target-on-human/)
- [In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors](https://scholariq.org/papers/in-vivo-gene-transfer-with-retroviral-vector-producer-cells-for-treatment-of/)
- [Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells](https://scholariq.org/papers/connecting-microrna-genes-to-the-core-transcriptional-regulatory-circuitry-of/)
- [Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease](https://scholariq.org/papers/standardized-rt-pcr-analysis-of-fusion-gene-transcripts-from-chromosome/)
- [Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma](https://scholariq.org/papers/curcumin-a-review-of-anti-cancer-properties-and-therapeutic-activity-in-head-and/)
- [Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome](https://scholariq.org/papers/lentiviral-hematopoietic-stem-cell-gene-therapy-in-patients-with-wiskott-aldrich/)
- [The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles](https://scholariq.org/papers/the-effect-of-surface-charge-on-in-vivo-biodistribution-of-peg-oligocholic-acid/)
- [p53 Activation by Knockdown Technologies](https://scholariq.org/papers/p53-activation-by-knockdown-technologies/)
- [A review on phospholipids and their main applications in drug delivery systems](https://scholariq.org/papers/a-review-on-phospholipids-and-their-main-applications-in-drug-delivery-systems/)
- [Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.](https://scholariq.org/papers/induction-of-interferon-gamma-production-by-natural-killer-cell-stimulatory/)

## Topic primary papers

Showing 15 of 55.

- [p53 Activation by Knockdown Technologies](https://scholariq.org/papers/p53-activation-by-knockdown-technologies/)
- [RNA interference in the clinic: challenges and future directions](https://scholariq.org/papers/rna-interference-in-the-clinic-challenges-and-future-directions/)
- [The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes](https://scholariq.org/papers/the-p21-src-genes-of-harvey-and-kirsten-sarcoma-viruses-originate-from-divergent/)
- [Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics](https://scholariq.org/papers/biodegradable-lipids-enabling-rapidly-eliminated-lipid-nanoparticles-for/)
- [A Small Interfering RNA Targeting Vascular Endothelial Growth Factor as Cancer Therapeutics](https://scholariq.org/papers/a-small-interfering-rna-targeting-vascular-endothelial-growth-factor-as-cancer/)
- [DNA nanostructures coordinate gene silencing in mature plants](https://scholariq.org/papers/dna-nanostructures-coordinate-gene-silencing-in-mature-plants/)
- [Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo.](https://scholariq.org/papers/studies-on-the-anti-tumor-efficacy-of-systemically-administered-recombinant/)
- [Gene Therapy Using TRAIL-Secreting Human Umbilical Cord Blood–Derived Mesenchymal Stem Cells against Intracranial Glioma](https://scholariq.org/papers/gene-therapy-using-trail-secreting-human-umbilical-cord-blood-derived/)
- [Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates](https://scholariq.org/papers/impact-of-enhanced-metabolic-stability-on-pharmacokinetics-and-pharmacodynamics/)
- [Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways](https://scholariq.org/papers/enhanced-intranasal-delivery-of-mrna-vaccine-by-overcoming-the-nasal-epithelial/)
- [Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier](https://scholariq.org/papers/systemic-brain-delivery-of-antisense-oligonucleotides-across-the-blood-brain/)
- [Materializing the Potential of Small Interfering RNA via a Tumor-Targeting Nanodelivery System](https://scholariq.org/papers/materializing-the-potential-of-small-interfering-rna-via-a-tumor-targeting/)
- [Effect of different chemically modified oligodeoxynucleotides on immune stimulation](https://scholariq.org/papers/effect-of-different-chemically-modified-oligodeoxynucleotides-on-immune/)
- [Amphibian Cell Culture: Permanent Cell Line from the Bullfrog ( <i>Rana catesbeiana</i> )](https://scholariq.org/papers/amphibian-cell-culture-permanent-cell-line-from-the-bullfrog-i-rana-catesbeiana/)
- [RGD-Tachyplesin inhibits tumor growth.](https://scholariq.org/papers/rgd-tachyplesin-inhibits-tumor-growth/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.