# RNA modifications and cancer

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/rna-modifications-and-cancer/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the diverse landscape of RNA methylation, with a focus on m6A modification, its impact on gene expression, ribosome biogenesis, and its role in cancer progression. The research covers various aspects such as m6A-seq, tRNA fragments, YTHDF proteins, and the involvement of methyltransferases in mRNA modification. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11482 |
| Works | 672 |

## Topic papers all

Showing 15 of 672.

- [An integrated encyclopedia of DNA elements in the human genome](https://scholariq.org/papers/an-integrated-encyclopedia-of-dna-elements-in-the-human-genome/)
- [The GTEx Consortium atlas of genetic regulatory effects across human tissues](https://scholariq.org/papers/the-gtex-consortium-atlas-of-genetic-regulatory-effects-across-human-tissues/)
- [The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis](https://scholariq.org/papers/the-tumour-suppressor-protein-vhl-targets-hypoxia-inducible-factors-for-oxygen/)
- [Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers](https://scholariq.org/papers/human-microrna-genes-are-frequently-located-at-fragile-sites-and-genomic-regions/)
- [A survey of best practices for RNA-seq data analysis](https://scholariq.org/papers/a-survey-of-best-practices-for-rna-seq-data-analysis/)
- [Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels](https://scholariq.org/papers/genome-wide-association-analysis-identifies-loci-for-type-2-diabetes-and/)
- [A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease](https://scholariq.org/papers/a-comprehensive-1000-genomes-based-genome-wide-association-meta-analysis-of/)
- [Expanded encyclopaedias of DNA elements in the human and mouse genomes](https://scholariq.org/papers/expanded-encyclopaedias-of-dna-elements-in-the-human-and-mouse-genomes/)
- [Systematic identification of genomic markers of drug sensitivity in cancer cells](https://scholariq.org/papers/systematic-identification-of-genomic-markers-of-drug-sensitivity-in-cancer-cells/)
- [Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma](https://scholariq.org/papers/comprehensive-and-integrative-genomic-characterization-of-hepatocellular/)
- [UALCAN: An update to the integrated cancer data analysis platform](https://scholariq.org/papers/ualcan-an-update-to-the-integrated-cancer-data-analysis-platform/)
- [International network of cancer genome projects](https://scholariq.org/papers/international-network-of-cancer-genome-projects/)
- [Lung Cancer](https://scholariq.org/papers/lung-cancer/)
- [A promoter-level mammalian expression atlas](https://scholariq.org/papers/a-promoter-level-mammalian-expression-atlas/)
- [Transcriptome and genome sequencing uncovers functional variation in humans](https://scholariq.org/papers/transcriptome-and-genome-sequencing-uncovers-functional-variation-in-humans/)

## Topic primary papers

Showing 15 of 147.

- [A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction](https://scholariq.org/papers/a-common-variant-on-chromosome-9p21-affects-the-risk-of-myocardial-infarction/)
- [Genetic mechanisms of critical illness in COVID-19](https://scholariq.org/papers/genetic-mechanisms-of-critical-illness-in-covid-19-2/)
- [Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion](https://scholariq.org/papers/targeting-fto-suppresses-cancer-stem-cell-maintenance-and-immune-evasion/)
- [MEG3 noncoding RNA: a tumor suppressor](https://scholariq.org/papers/meg3-noncoding-rna-a-tumor-suppressor/)
- [WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1](https://scholariq.org/papers/wtap-facilitates-progression-of-hepatocellular-carcinoma-via-m6a-hur-dependent/)
- [Aberrant methylation of tRNAs links cellular stress to neuro‐developmental disorders](https://scholariq.org/papers/aberrant-methylation-of-trnas-links-cellular-stress-to-neuro-developmental/)
- [ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment](https://scholariq.org/papers/alkbh5-regulates-anti-pd-1-therapy-response-by-modulating-lactate-and/)
- [deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data](https://scholariq.org/papers/defuse-an-algorithm-for-gene-fusion-discovery-in-tumor-rna-seq-data/)
- [METTL3 and ALKBH5 oppositely regulate m<sup>6</sup>A modification of <i>TFEB</i> mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes](https://scholariq.org/papers/mettl3-and-alkbh5-oppositely-regulate-m-sup-6-sup-a-modification-of-i-tfeb-i/)
- [METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer](https://scholariq.org/papers/mettl3-igf2bp3-axis-inhibits-tumor-immune-surveillance-by-upregulating-n6/)
- [Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations](https://scholariq.org/papers/whole-exome-sequencing-identifies-recessive-wdr62-mutations-in-severe-brain/)
- [Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase](https://scholariq.org/papers/functional-screen-reveals-sars-coronavirus-nonstructural-protein-nsp14-as-a/)
- [RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner](https://scholariq.org/papers/rna-demethylase-alkbh5-prevents-pancreatic-cancer-progression-by/)
- [RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming](https://scholariq.org/papers/rna-m6a-methylation-orchestrates-cancer-growth-and-metastasis-via-macrophage/)
- [Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma](https://scholariq.org/papers/endogenous-retrotransposition-activates-oncogenic-pathways-in-hepatocellular/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.