# Signaling Pathways in Disease

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/signaling-pathways-in-disease-2/

## Facts

| Field | Value |
| --- | --- |
| Citations | 991,785 |
| Description | This cluster of papers focuses on the role of Calcineurin-NFAT signaling in transcriptional regulation, with a particular emphasis on its involvement in cancer progression, cardiac hypertrophy, and inflammatory responses. The cluster also explores the impact of Prolyl Isomerase Pin1, EMMPRIN/CD147, and immunophilins in modulating this signaling pathway. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | https://openalex.org/T12620 |
| Works | 37,284 |

## Topic researchers

Showing 12 of 20.

- [Eric S. Lander](https://scholariq.org/researchers/eric-s-lander/)
- [Mark J. Daly](https://scholariq.org/researchers/mark-j-daly/)
- [Guido Kroemer](https://scholariq.org/researchers/guido-kroemer/)
- [John J.V. McMurray](https://scholariq.org/researchers/john-j-v-mcmurray/)
- [Shizuo Akira](https://scholariq.org/researchers/shizuo-akira/)
- [Salim Yusuf](https://scholariq.org/researchers/salim-yusuf/)
- [Todd R. Golub](https://scholariq.org/researchers/todd-r-golub/)
- [Michael Karin](https://scholariq.org/researchers/michael-karin/)
- [Hagop M. Kantarjian](https://scholariq.org/researchers/hagop-m-kantarjian/)
- [Gordon B. Mills](https://scholariq.org/researchers/gordon-b-mills/)
- [Piotr Ponikowski](https://scholariq.org/researchers/piotr-ponikowski/)
- [Richard A. Flavell](https://scholariq.org/researchers/richard-a-flavell/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.