# Sirtuins and Resveratrol in Medicine

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/sirtuins-and-resveratrol-in-medicine/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of sirtuins, particularly SIRT1-7, in regulating metabolism, aging, and cellular homeostasis. It investigates the impact of resveratrol, NAD+, calorie restriction, and oxidative stress on sirtuin activity and their implications for longevity and age-related diseases. The cluster also delves into the interplay between sirtuins, mitochondria, and cellular energy balance. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t11051 |
| Works | 192 |

## Topic papers all

Showing 15 of 192.

- [Resveratrol: A Double-Edged Sword in Health Benefits](https://scholariq.org/papers/resveratrol-a-double-edged-sword-in-health-benefits/)
- [Plant Foods and Herbal Sources of Resveratrol](https://scholariq.org/papers/plant-foods-and-herbal-sources-of-resveratrol/)
- [NAD+ metabolism in health and disease](https://scholariq.org/papers/nad-metabolism-in-health-and-disease/)
- [Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1](https://scholariq.org/papers/adiponectin-and-adipor1-regulate-pgc-1-and-mitochondria-by-ca2-and-ampk-sirt1/)
- [Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme](https://scholariq.org/papers/nampt-pbef-visfatin-regulates-insulin-secretion-in-cells-as-a-systemic-nad/)
- [The sirtuin family in health and disease](https://scholariq.org/papers/the-sirtuin-family-in-health-and-disease/)
- [Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice](https://scholariq.org/papers/impaired-dna-damage-response-genome-instability-and-tumorigenesis-in-sirt1/)
- [Discoveries of Nicotinamide Riboside as a Nutrient and Conserved NRK Genes Establish a Preiss-Handler Independent Route to NAD+ in Fungi and Humans](https://scholariq.org/papers/discoveries-of-nicotinamide-riboside-as-a-nutrient-and-conserved-nrk-genes/)
- [Nicotinamide riboside is uniquely and orally bioavailable in mice and humans](https://scholariq.org/papers/nicotinamide-riboside-is-uniquely-and-orally-bioavailable-in-mice-and-humans/)
- [Physiological and pathophysiological roles of NAMPT and NAD metabolism](https://scholariq.org/papers/physiological-and-pathophysiological-roles-of-nampt-and-nad-metabolism/)
- [Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD<sup>+</sup> Precursor Vitamins in Human Nutrition](https://scholariq.org/papers/nicotinic-acid-nicotinamide-and-nicotinamide-riboside-a-molecular-evaluation-of/)
- [Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney](https://scholariq.org/papers/calorie-restriction-enhances-cell-adaptation-to-hypoxia-through-sirt1-dependent/)
- [Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion](https://scholariq.org/papers/silent-information-regulator-1-protects-the-heart-from-ischemia-reperfusion/)
- [PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection](https://scholariq.org/papers/pgc1-drives-nad-biosynthesis-linking-oxidative-metabolism-to-renal-protection/)
- [Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target](https://scholariq.org/papers/mitochondrial-sirtuin-3-new-emerging-biological-function-and-therapeutic-target/)

## Topic primary papers

Showing 15 of 110.

- [Resveratrol: A Double-Edged Sword in Health Benefits](https://scholariq.org/papers/resveratrol-a-double-edged-sword-in-health-benefits/)
- [Plant Foods and Herbal Sources of Resveratrol](https://scholariq.org/papers/plant-foods-and-herbal-sources-of-resveratrol/)
- [Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme](https://scholariq.org/papers/nampt-pbef-visfatin-regulates-insulin-secretion-in-cells-as-a-systemic-nad/)
- [The sirtuin family in health and disease](https://scholariq.org/papers/the-sirtuin-family-in-health-and-disease/)
- [Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice](https://scholariq.org/papers/impaired-dna-damage-response-genome-instability-and-tumorigenesis-in-sirt1/)
- [Physiological and pathophysiological roles of NAMPT and NAD metabolism](https://scholariq.org/papers/physiological-and-pathophysiological-roles-of-nampt-and-nad-metabolism/)
- [Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney](https://scholariq.org/papers/calorie-restriction-enhances-cell-adaptation-to-hypoxia-through-sirt1-dependent/)
- [Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion](https://scholariq.org/papers/silent-information-regulator-1-protects-the-heart-from-ischemia-reperfusion/)
- [Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes](https://scholariq.org/papers/renal-tubular-sirt1-attenuates-diabetic-albuminuria-by-epigenetically/)
- [SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production](https://scholariq.org/papers/sirt3-deacetylates-mitochondrial-3-hydroxy-3-methylglutaryl-coa-synthase-2-and/)
- [Metabolism and Disposition of Resveratrol in Rats: Extent of Absorption, Glucuronidation, and Enterohepatic Recirculation Evidenced by a Linked-Rat Model](https://scholariq.org/papers/metabolism-and-disposition-of-resveratrol-in-rats-extent-of-absorption/)
- [Resveratrol for cancer therapy: Challenges and future perspectives](https://scholariq.org/papers/resveratrol-for-cancer-therapy-challenges-and-future-perspectives/)
- [Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures](https://scholariq.org/papers/nicotinamide-riboside-augments-the-aged-human-skeletal-muscle-nad-metabolome-and/)
- [Nicotinamide Riboside Promotes Sir2 Silencing and Extends Lifespan via Nrk and Urh1/Pnp1/Meu1 Pathways to NAD+](https://scholariq.org/papers/nicotinamide-riboside-promotes-sir2-silencing-and-extends-lifespan-via-nrk-and/)
- [SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability](https://scholariq.org/papers/sirt7-is-a-histone-desuccinylase-that-functionally-links-to-chromatin-compaction/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.