# Synthesis and biological activity

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/synthesis-and-biological-activity/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the synthesis, biological activities, and therapeutic potential of heterocyclic compounds, particularly in the context of drug discovery. The research covers a wide range of applications, including the development of anticancer agents, tubulin inhibitors, vascular targeting agents, and anti-inflammatory/antioxidant compounds. |
| Domain | Physical Sciences |
| Field | Chemistry |
| OpenAlex ID | t10274 |
| Works | 52 |

## Topic papers all

Showing 15 of 52.

- [Flavonoids: antioxidants or signalling molecules?](https://scholariq.org/papers/flavonoids-antioxidants-or-signalling-molecules/)
- [Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial](https://scholariq.org/papers/dabrafenib-plus-trametinib-in-patients-with-previously-untreated-brafv600e/)
- [Dabrafenib plus trametinib in patients with previously treated BRAFV600E-mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial](https://scholariq.org/papers/dabrafenib-plus-trametinib-in-patients-with-previously-treated-brafv600e-mutant/)
- [Multi-targeted prevention of cancer by sulforaphane](https://scholariq.org/papers/multi-targeted-prevention-of-cancer-by-sulforaphane/)
- [Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species](https://scholariq.org/papers/sulforaphane-induced-cell-death-in-human-prostate-cancer-cells-is-initiated-by/)
- [Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde](https://scholariq.org/papers/synthesis-and-antimicrobial-activities-of-schiff-bases-derived-from-5-chloro/)
- [Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities](https://scholariq.org/papers/synthesis-of-biscoumarin-and-dihydropyran-derivatives-with-promising-antitumor/)
- [Recent development on COX-2 inhibitors as promising anti-inflammatory agents: The past 10 years](https://scholariq.org/papers/recent-development-on-cox-2-inhibitors-as-promising-anti-inflammatory-agents-the/)
- [Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications](https://scholariq.org/papers/triazoles-and-their-derivatives-chemistry-synthesis-and-therapeutic-applications/)
- [Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents](https://scholariq.org/papers/synthesis-and-evaluation-of-a-class-of-new-coumarin-triazole-derivatives-as/)
- [Benzotriazole: An overview on its versatile biological behavior](https://scholariq.org/papers/benzotriazole-an-overview-on-its-versatile-biological-behavior/)
- [Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani](https://scholariq.org/papers/reversal-of-multidrug-resistance-in-cancer-cells-by-pyranocoumarins-isolated/)
- [Digitoxin Inhibits the Growth of Cancer Cell Lines at Concentrations Commonly Found in Cardiac Patients](https://scholariq.org/papers/digitoxin-inhibits-the-growth-of-cancer-cell-lines-at-concentrations-commonly/)
- [Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines](https://scholariq.org/papers/synthesis-and-antiplasmodial-activity-of-new-4-aryl-2/)
- [Synthesis, crystal structure, cytotoxic activity and DNA-binding properties of the copper (II) and zinc (II) complexes with 1-\[3-(2-pyridyl)pyrazol-1-ylmethyl\]naphthalene](https://scholariq.org/papers/synthesis-crystal-structure-cytotoxic-activity-and-dna-binding-properties-of-the/)

## Topic primary papers

- [Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde](https://scholariq.org/papers/synthesis-and-antimicrobial-activities-of-schiff-bases-derived-from-5-chloro/)
- [Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities](https://scholariq.org/papers/synthesis-of-biscoumarin-and-dihydropyran-derivatives-with-promising-antitumor/)
- [Benzotriazole: An overview on its versatile biological behavior](https://scholariq.org/papers/benzotriazole-an-overview-on-its-versatile-biological-behavior/)
- [CONVULSANT ACTIVITY OF HOMOCYSTEINE AND OTHER SHORT-CHAIN MERCAPTOACIDS: PROTECTION THEREFROM](https://scholariq.org/papers/convulsant-activity-of-homocysteine-and-other-short-chain-mercaptoacids/)
- [CONVULSANT ACTIVITY OF HOMOCYSTEINE AND OTHER SHORT-CHAIN MERCAPTOACIDS: PROTECTION THEREFROM](https://scholariq.org/papers/convulsant-activity-of-homocysteine-and-other-short-chain-mercaptoacids-2/)
- [Advances in 2‐substituted benzothiazole scaffold‐based chemotherapeutic agents](https://scholariq.org/papers/advances-in-2-substituted-benzothiazole-scaffold-based-chemotherapeutic-agents/)
- [Multitarget Molecular Hybrids of Cinnamic Acids](https://scholariq.org/papers/multitarget-molecular-hybrids-of-cinnamic-acids/)
- [The Anticancer Activity of Indazole Compounds: A Mini Review](https://scholariq.org/papers/the-anticancer-activity-of-indazole-compounds-a-mini-review/)
- [Design, synthesis and characterization of new fused pyrazole systems: In Vitro anti-bacterial, anti-fungal, antioxidant evaluation, In Silico DFT and molecular docking studies](https://scholariq.org/papers/design-synthesis-and-characterization-of-new-fused-pyrazole-systems-in-vitro/)
- [Design, synthesis, characterization and fluorescence property evaluation of dehydroacetic acid-based chalcones](https://scholariq.org/papers/design-synthesis-characterization-and-fluorescence-property-evaluation-of/)
- [Synthesis of New Benzoxazole Derivatives and Evaluation of their Antifungal and Antibacterial Activities](https://scholariq.org/papers/synthesis-of-new-benzoxazole-derivatives-and-evaluation-of-their-antifungal-and/)
- [ChemInform Abstract: 2‐(3‐Pyridyl)thiazolidine‐4‐carboxamides. Part 1. Novel Orally Active Antagonists of Platelet‐Activating Factor (PAF).](https://scholariq.org/papers/cheminform-abstract-2-3-pyridyl-thiazolidine-4-carboxamides-part-1-novel-orally/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.