# Synthesis and pharmacology of benzodiazepine derivatives

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/synthesis-and-pharmacology-of-benzodiazepine-derivatives/

## Facts

| Field | Value |
| --- | --- |
| Citations | 99,936 |
| Description | This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis. |
| Domain | Physical Sciences |
| Field | Chemistry |
| OpenAlex ID | https://openalex.org/T13105 |
| Works | 17,826 |

## Topic papers all

- [BENZODIAZEPINE-LIKE CENTRAL EFFECTS OF R.P. 27 267, A DIHYDRO-7-OXO-5H-PYRROLO \[3,4-b\] PYRAZINE DERIVATIVE](https://scholariq.org/papers/benzodiazepine-like-central-effects-of-r-p-27-267-a-dihydro-7-oxo-5h-pyrrolo-3-4/)
- [RP 59037 and RP 60503: anxiolytic cyclopyrrolone derivatives with low sedative potential. interaction with the gamma-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent.](https://scholariq.org/papers/rp-59037-and-rp-60503-anxiolytic-cyclopyrrolone-derivatives-with-low-sedative/)
- [A Case of Lurasidone-Induced Urinary Retention](https://scholariq.org/papers/a-case-of-lurasidone-induced-urinary-retention/)

## Topic researchers

Showing 12 of 20.

- [Gabriel N. Hortobágyi](https://scholariq.org/researchers/gabriel-n-hortobagyi/)
- [Yves Pommier](https://scholariq.org/researchers/yves-pommier/)
- [Alan R. Katritzky](https://scholariq.org/researchers/alan-r-katritzky/)
- [Robert A. Koeppe](https://scholariq.org/researchers/robert-a-koeppe/)
- [Jacqueline N. Crawley](https://scholariq.org/researchers/jacqueline-n-crawley/)
- [Jau‐Shyong Hong](https://scholariq.org/researchers/jau-shyong-hong/)
- [Richard C. Larock](https://scholariq.org/researchers/richard-c-larock/)
- [Shaomeng Wang](https://scholariq.org/researchers/shaomeng-wang/)
- [Irwin J. Kopin](https://scholariq.org/researchers/irwin-j-kopin/)
- [Jonathan A. Ellman](https://scholariq.org/researchers/jonathan-a-ellman/)
- [Edward A. Sausville](https://scholariq.org/researchers/edward-a-sausville/)
- [Sylvain Houle](https://scholariq.org/researchers/sylvain-houle/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.