# T-cell and B-cell Immunology
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/t-cell-and-b-cell-immunology/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the development, function, and regulation of regulatory T cells (Tregs), particularly emphasizing the role of transcription factor Foxp3, TGF-ß induction, immune tolerance, thymic selection, memory T cells, IL-2 signaling, and their involvement in tumor immunity and immunological surveillance. The cluster also explores the implications of Tregs in autoimmunity and their potential for therapeutic interventions. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t10031 |
| Works | 572 |
## Topic papers all
Showing 15 of 572.
- [The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer](https://scholariq.org/papers/the-role-of-tumoral-foxp3-on-cell-proliferation-migration-and-invasion-in/)
- [Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus](https://scholariq.org/papers/interferon-inducible-gene-expression-signature-in-peripheral-blood-cells-of/)
- [Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation](https://scholariq.org/papers/effects-of-a-polymorphism-in-the-human-tumor-necrosis-factor-promoter-on/)
- [Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease](https://scholariq.org/papers/association-of-the-t-cell-regulatory-gene-ctla4-with-susceptibility-to/)
- [Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.](https://scholariq.org/papers/identification-and-purification-of-natural-killer-cell-stimulatory-factor-nksf-a/)
- [Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer](https://scholariq.org/papers/successful-adoptive-transfer-and-in-vivo-expansion-of-human-haploidentical-nk/)
- [Phenotypic and functional features of human Th17 cells](https://scholariq.org/papers/phenotypic-and-functional-features-of-human-th17-cells/)
- [Systemic Lupus Erythematosus](https://scholariq.org/papers/systemic-lupus-erythematosus-6/)
- [Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma](https://scholariq.org/papers/cancer-regression-and-autoimmunity-induced-by-cytotoxic-t-lymphocyte-associated/)
- [CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients](https://scholariq.org/papers/cd19-cd24hicd38hi-b-cells-exhibit-regulatory-capacity-in-healthy-individuals-but/)
- [The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract](https://scholariq.org/papers/the-chemokine-receptor-cxcr4-is-essential-for-vascularization-of-the/)
- [Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility](https://scholariq.org/papers/multiple-sclerosis-genomic-map-implicates-peripheral-immune-cells-and-microglia/)
- [Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry](https://scholariq.org/papers/defining-inflammatory-cell-states-in-rheumatoid-arthritis-joint-synovial-tissues/)
- [CD40-CD40 ligand](https://scholariq.org/papers/cd40-cd40-ligand/)
- [Efficacy and safety of rituximab in moderately‐to‐severely active systemic lupus erythematosus: The randomized, double‐blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial](https://scholariq.org/papers/efficacy-and-safety-of-rituximab-in-moderately-to-severely-active-systemic-lupus/)
## Topic primary papers
Showing 15 of 89.
- [The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer](https://scholariq.org/papers/the-role-of-tumoral-foxp3-on-cell-proliferation-migration-and-invasion-in/)
- [Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma](https://scholariq.org/papers/cancer-regression-and-autoimmunity-induced-by-cytotoxic-t-lymphocyte-associated/)
- [CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients](https://scholariq.org/papers/cd19-cd24hicd38hi-b-cells-exhibit-regulatory-capacity-in-healthy-individuals-but/)
- [Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility](https://scholariq.org/papers/multiple-sclerosis-genomic-map-implicates-peripheral-immune-cells-and-microglia/)
- [Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry](https://scholariq.org/papers/defining-inflammatory-cell-states-in-rheumatoid-arthritis-joint-synovial-tissues/)
- [The CD40 Antigen and its Ligand](https://scholariq.org/papers/the-cd40-antigen-and-its-ligand/)
- [Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy](https://scholariq.org/papers/compromised-function-of-regulatory-t-cells-in-rheumatoid-arthritis-and-reversal/)
- [Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus](https://scholariq.org/papers/distinct-effector-b-cells-induced-by-unregulated-toll-like-receptor-7-contribute/)
- [Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy](https://scholariq.org/papers/age-thymopoiesis-and-cd4-t-lymphocyte-regeneration-after-intensive-chemotherapy/)
- [Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells](https://scholariq.org/papers/fibroblastic-reticular-cells-in-lymph-nodes-regulate-the-homeostasis-of-naive-t/)
- [Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys](https://scholariq.org/papers/expanded-double-negative-t-cells-in-patients-with-systemic-lupus-erythematosus/)
- [Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer](https://scholariq.org/papers/regulatory-t-cells-exhibit-distinct-features-in-human-breast-cancer/)
- [Identification of IL-17-producing FOXP3 + regulatory T cells in humans](https://scholariq.org/papers/identification-of-il-17-producing-foxp3-sup-sup-regulatory-t-cells-in-humans/)
- [CD19 + CD24 hi CD38 hi B Cells Maintain Regulatory T Cells While Limiting T H 1 and T H 17 Differentiation](https://scholariq.org/papers/cd19-sup-sup-cd24-sup-hi-sup-cd38-sup-hi-sup-b-cells-maintain-regulatory-t-cells/)
- [Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis](https://scholariq.org/papers/novel-suppressive-function-of-transitional-2-b-cells-in-experimental-arthritis/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.