# Toxin Mechanisms and Immunotoxins

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/toxin-mechanisms-and-immunotoxins/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the development and efficacy of immunotoxin therapy for cancer treatment, with a particular emphasis on ricin poisoning, ribosome-inactivating proteins, and targeted therapy using recombinant immunotoxins. It also explores the use of IL-13 receptor and mistletoe extract in cancer therapy. |
| Domain | Life Sciences |
| Field | Immunology and Microbiology |
| OpenAlex ID | t12477 |
| Works | 102 |

## Topic papers all

Showing 15 of 102.

- [Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer](https://scholariq.org/papers/olaparib-plus-bevacizumab-as-first-line-maintenance-in-ovarian-cancer/)
- [Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis](https://scholariq.org/papers/fibroblast-like-synoviocytes-key-effector-cells-in-rheumatoid-arthritis/)
- [Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo](https://scholariq.org/papers/blockade-of-interleukin-6-trans-signaling-suppresses-t-cell-resistance-against/)
- [IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis](https://scholariq.org/papers/il-13-signaling-through-the-il-13-2-receptor-is-involved-in-induction-of-tgf-1/)
- [Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides](https://scholariq.org/papers/interleukin-6-in-synovial-fluid-and-serum-of-patients-with-rheumatoid-arthritis/)
- [Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes.](https://scholariq.org/papers/cytotoxic-t-lymphocyte-granules-are-secretory-lysosomes-containing-both-perforin/)
- [Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.](https://scholariq.org/papers/wortmannin-a-potent-and-selective-inhibitor-of-phosphatidylinositol-3-kinase/)
- [Phase I Trial of Interleukin-12 Plasmid Electroporation in Patients With Metastatic Melanoma](https://scholariq.org/papers/phase-i-trial-of-interleukin-12-plasmid-electroporation-in-patients-with/)
- [Ricin Poisoning](https://scholariq.org/papers/ricin-poisoning/)
- [Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.](https://scholariq.org/papers/identification-of-an-11-kda-fkbp12-rapamycin-binding-domain-within-the-289-kda/)
- [Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast](https://scholariq.org/papers/exploring-the-mode-of-action-of-bioactive-compounds-by-chemical-genetic/)
- [Steroid receptors and their associated proteins.](https://scholariq.org/papers/steroid-receptors-and-their-associated-proteins/)
- [Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma](https://scholariq.org/papers/blockade-of-xbp1-splicing-by-inhibition-of-ire1-is-a-promising-therapeutic/)
- [The Hsp90‐binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo](https://scholariq.org/papers/the-hsp90-binding-peptidylprolyl-isomerase-fkbp52-potentiates-glucocorticoid/)
- [Identification and Characterization of Galectin-9, a Novel β-Galactoside-binding Mammalian Lectin](https://scholariq.org/papers/identification-and-characterization-of-galectin-9-a-novel-galactoside-binding/)

## Topic primary papers

Showing 15 of 19.

- [IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis](https://scholariq.org/papers/il-13-signaling-through-the-il-13-2-receptor-is-involved-in-induction-of-tgf-1/)
- [Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.](https://scholariq.org/papers/wortmannin-a-potent-and-selective-inhibitor-of-phosphatidylinositol-3-kinase/)
- [Ricin Poisoning](https://scholariq.org/papers/ricin-poisoning/)
- [The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer](https://scholariq.org/papers/the-spirochetal-etiology-of-acrodermatitis-chronica-atrophicans-herxheimer/)
- [The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13–induced signal transduction through the STAT6 pathway](https://scholariq.org/papers/the-interleukin-13-receptor-2-chain-an-essential-component-for-binding-and/)
- [Viscum album \[L.\] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival](https://scholariq.org/papers/viscum-album-l-extract-therapy-in-patients-with-locally-advanced-or-metastatic/)
- [The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex](https://scholariq.org/papers/the-cytosolic-entry-of-diphtheria-toxin-catalytic-domain-requires-a-host-cell/)
- [Iron, DtxR, and the regulation of diphtheria toxin expression](https://scholariq.org/papers/iron-dtxr-and-the-regulation-of-diphtheria-toxin-expression/)
- [Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells <sup>1</sup>](https://scholariq.org/papers/damage-to-nuclear-dna-induced-by-shiga-toxin-1-and-ricin-in-human-endothelial/)
- [Apoptosis induced by Staphylococcus aureus toxins](https://scholariq.org/papers/apoptosis-induced-by-staphylococcus-aureus-toxins/)
- [Shock wave permeabilization with ribosome inactivating proteins: a new approach to tumor therapy.](https://scholariq.org/papers/shock-wave-permeabilization-with-ribosome-inactivating-proteins-a-new-approach/)
- [Structure Function Analysis of an ADP-ribosyltransferase Type III Effector and Its RNA-binding Target in Plant Immunity](https://scholariq.org/papers/structure-function-analysis-of-an-adp-ribosyltransferase-type-iii-effector-and/)
- [European Viscum album: a potent phytotherapeutic agent with multifarious phytochemicals, pharmacological properties and clinical evidence](https://scholariq.org/papers/european-viscum-album-a-potent-phytotherapeutic-agent-with-multifarious/)
- [Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells](https://scholariq.org/papers/involvement-of-hydrogen-peroxide-in-mistletoe-lectin-ii-induced-apoptosis-of/)
- [Quality of Life of Patients With Advanced Pancreatic Cancer During Treatment With Mistletoe](https://scholariq.org/papers/quality-of-life-of-patients-with-advanced-pancreatic-cancer-during-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.