# Tuberous Sclerosis Complex Research

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/tuberous-sclerosis-complex-research/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on Tuberous Sclerosis Complex (TSC) and related disorders, including Lymphangioleiomyomatosis and Angiomyolipoma. It covers various aspects such as genetic mutations, neurological manifestations, use of mTOR inhibitors, diagnostic criteria, and the role of hamartin and tuberin proteins. Additionally, it explores the association with epilepsy and cognitive impairment. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t12049 |
| Works | 113 |

## Topic papers all

Showing 15 of 113.

- [Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma](https://scholariq.org/papers/temsirolimus-interferon-alfa-or-both-for-advanced-renal-cell-carcinoma/)
- [The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1](https://scholariq.org/papers/the-clinicopathologic-spectrum-of-focal-cortical-dysplasias-a-consensus/)
- [Tuberous Sclerosis Complex Diagnostic Criteria Update: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference](https://scholariq.org/papers/tuberous-sclerosis-complex-diagnostic-criteria-update-recommendations-of-the/)
- [Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis](https://scholariq.org/papers/sirolimus-for-angiomyolipoma-in-tuberous-sclerosis-complex-or/)
- [Terminology and classification of the cortical dysplasias](https://scholariq.org/papers/terminology-and-classification-of-the-cortical-dysplasias/)
- [Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome](https://scholariq.org/papers/mutations-in-a-novel-gene-lead-to-kidney-tumors-lung-wall-defects-and-benign/)
- [Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial](https://scholariq.org/papers/everolimus-for-angiomyolipoma-associated-with-tuberous-sclerosis-complex-or/)
- [Tuberous Sclerosis Complex Surveillance and Management: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference](https://scholariq.org/papers/tuberous-sclerosis-complex-surveillance-and-management-recommendations-of-the/)
- [Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation](https://scholariq.org/papers/revised-diagnostic-criteria-for-neurofibromatosis-type-1-and-legius-syndrome-an/)
- [Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study](https://scholariq.org/papers/adjunctive-everolimus-therapy-for-treatment-resistant-focal-onset-seizures/)
- [Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations](https://scholariq.org/papers/updated-international-tuberous-sclerosis-complex-diagnostic-criteria-and/)
- [Activity of Selumetinib in Neurofibromatosis Type 1–Related Plexiform Neurofibromas](https://scholariq.org/papers/activity-of-selumetinib-in-neurofibromatosis-type-1-related-plexiform/)
- [Renal Tumors in the Birt-Hogg-Dubé Syndrome](https://scholariq.org/papers/renal-tumors-in-the-birt-hogg-dube-syndrome/)
- [Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma](https://scholariq.org/papers/antitumor-activity-of-rapamycin-in-a-phase-i-trial-for-patients-with-recurrent/)
- [Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease](https://scholariq.org/papers/everolimus-in-patients-with-autosomal-dominant-polycystic-kidney-disease/)

## Topic primary papers

Showing 15 of 31.

- [Tuberous Sclerosis Complex Diagnostic Criteria Update: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference](https://scholariq.org/papers/tuberous-sclerosis-complex-diagnostic-criteria-update-recommendations-of-the/)
- [Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis](https://scholariq.org/papers/sirolimus-for-angiomyolipoma-in-tuberous-sclerosis-complex-or/)
- [Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial](https://scholariq.org/papers/everolimus-for-angiomyolipoma-associated-with-tuberous-sclerosis-complex-or/)
- [Tuberous Sclerosis Complex Surveillance and Management: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference](https://scholariq.org/papers/tuberous-sclerosis-complex-surveillance-and-management-recommendations-of-the/)
- [Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study](https://scholariq.org/papers/adjunctive-everolimus-therapy-for-treatment-resistant-focal-onset-seizures/)
- [Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations](https://scholariq.org/papers/updated-international-tuberous-sclerosis-complex-diagnostic-criteria-and/)
- [Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway](https://scholariq.org/papers/pancreatic-endocrine-tumors-expression-profiling-evidences-a-role-for-akt-mtor/)
- [A Distinctive Subset of PEComas Harbors TFE3 Gene Fusions](https://scholariq.org/papers/a-distinctive-subset-of-pecomas-harbors-tfe3-gene-fusions/)
- [Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade](https://scholariq.org/papers/mammalian-target-of-rapamycin-regulates-murine-and-human-cell-differentiation/)
- [Randomized trial of vigabatrin in patients with infantile spasms](https://scholariq.org/papers/randomized-trial-of-vigabatrin-in-patients-with-infantile-spasms/)
- [Small (<4 cm) Renal Mass: Differentiation of Angiomyolipoma without Visible Fat from Renal Cell Carcinoma Utilizing MR Imaging](https://scholariq.org/papers/small-and-lt-4-cm-renal-mass-differentiation-of-angiomyolipoma-without-visible/)
- [Early-Life Epilepsies and the Emerging Role of Genetic Testing](https://scholariq.org/papers/early-life-epilepsies-and-the-emerging-role-of-genetic-testing/)
- [The Tuberous Sclerosis Complex and its Highly Variable Manifestations](https://scholariq.org/papers/the-tuberous-sclerosis-complex-and-its-highly-variable-manifestations/)
- [Presentation and Diagnosis of Tuberous Sclerosis Complex in Infants](https://scholariq.org/papers/presentation-and-diagnosis-of-tuberous-sclerosis-complex-in-infants/)
- [A systematic review on the burden of illness in individuals with tuberous sclerosis complex (TSC)](https://scholariq.org/papers/a-systematic-review-on-the-burden-of-illness-in-individuals-with-tuberous/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.