# vaccines and immunoinformatics approaches

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/vaccines-and-immunoinformatics-approaches/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the prediction of peptide-major histocompatibility complex (MHC) binding affinity, epitope prediction, and immunoinformatics for vaccine design. It covers topics such as antigen presentation, HLA class I and II molecules, bioinformatics tools for epitope prediction, T-cell and B-cell epitopes, and proteasomal cleavage. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12576 |
| Works | 92 |

## Topic papers all

Showing 15 of 92.

- [Genome sequence of the human malaria parasite Plasmodium falciparum](https://scholariq.org/papers/genome-sequence-of-the-human-malaria-parasite-plasmodium-falciparum/)
- [Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial](https://scholariq.org/papers/safety-and-immunogenicity-of-the-chadox1-ncov-19-vaccine-against-sars-cov-2-a/)
- [Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods](https://scholariq.org/papers/analysis-of-therapeutic-targets-for-sars-cov-2-and-discovery-of-potential-drugs/)
- [Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma](https://scholariq.org/papers/immunologic-and-therapeutic-evaluation-of-a-synthetic-peptide-vaccine-for-the/)
- [The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity](https://scholariq.org/papers/the-impact-of-mutations-in-sars-cov-2-spike-on-viral-infectivity-and/)
- [Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1](https://scholariq.org/papers/tumor-regression-in-patients-with-metastatic-synovial-cell-sarcoma-and-melanoma/)
- [Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution](https://scholariq.org/papers/allele-specific-hla-loss-and-immune-escape-in-lung-cancer-evolution/)
- [Activation of human dendritic cells through CD40 cross-linking.](https://scholariq.org/papers/activation-of-human-dendritic-cells-through-cd40-cross-linking/)
- [Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine](https://scholariq.org/papers/phase-1-2-trial-of-a-sars-cov-2-recombinant-spike-protein-nanoparticle-vaccine/)
- [Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy](https://scholariq.org/papers/patient-hla-class-i-genotype-influences-cancer-response-to-checkpoint-blockade/)
- [Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review](https://scholariq.org/papers/comparing-covid-19-vaccines-for-their-characteristics-efficacy-and-effectiveness/)
- [Dynamics and Function of Langerhans Cells In Vivo](https://scholariq.org/papers/dynamics-and-function-of-langerhans-cells-in-vivo/)
- [gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma](https://scholariq.org/papers/gp100-peptide-vaccine-and-interleukin-2-in-patients-with-advanced-melanoma/)
- [Molecular signatures of antibody responses derived from a systems biology study of five human vaccines](https://scholariq.org/papers/molecular-signatures-of-antibody-responses-derived-from-a-systems-biology-study/)
- [A Bivalent Omicron-Containing Booster Vaccine against Covid-19](https://scholariq.org/papers/a-bivalent-omicron-containing-booster-vaccine-against-covid-19/)

## Topic primary papers

- [Molecular signatures of antibody responses derived from a systems biology study of five human vaccines](https://scholariq.org/papers/molecular-signatures-of-antibody-responses-derived-from-a-systems-biology-study/)
- [HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy](https://scholariq.org/papers/hla-ligand-atlas-a-benign-reference-of-hla-presented-peptides-to-improve-t-cell/)
- [Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes](https://scholariq.org/papers/systematically-benchmarking-peptide-mhc-binding-predictors-from-synthetic-to/)
- [DLpTCR: an ensemble deep learning framework for predicting immunogenic peptide recognized by T cell receptor](https://scholariq.org/papers/dlptcr-an-ensemble-deep-learning-framework-for-predicting-immunogenic-peptide/)
- [ParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures](https://scholariq.org/papers/parapep-a-web-resource-for-experimentally-validated-antiparasitic-peptide/)
- [Epitope based vaccine prediction for SARS-COV-2 by deploying immuno-informatics approach](https://scholariq.org/papers/epitope-based-vaccine-prediction-for-sars-cov-2-by-deploying-immuno-informatics/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.