Papers.

• The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease 1,873 citations
• 2. Diagnosis and Classification of Diabetes:<i>Standards of Care in Diabetes—2024</i> 1,873 citations
• Role of Genes and Environments for Explaining Alzheimer Disease 1,872 citations
• Cardiovascular Disease in Chronic Kidney Disease 1,872 citations
• Effects of Treating Depression and Low Perceived Social Support on Clinical Events After Myocardial Infarction 1,871 citations
• The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis 1,870 citations
• Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma 1,870 citations
• STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors 1,869 citations
• Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study 1,868 citations
• Heteroatom-doped graphene materials: syntheses, properties and applications 1,868 citations
• Schizophrenia 1,868 citations
• Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline 1,866 citations
• Ankle Brachial Index Combined With Framingham Risk Score to Predict Cardiovascular Events and Mortality 1,866 citations
• Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents 1,865 citations
• The malleability of spatial skills: A meta-analysis of training studies. 1,865 citations
• Dynamic Statistical Parametric Mapping 1,864 citations
• Systematic review of the application of the plan–do–study–act method to improve quality in healthcare 1,864 citations
• A questionnaire for the assessment of leisure time physical activities 1,864 citations
• TIMI Frame Count 1,863 citations
• The PRECIS-2 tool: designing trials that are fit for purpose 1,862 citations
• Interpretation of the evidence for the efficacy and safety of statin therapy 1,862 citations
• Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. 1,861 citations
• Service Innovation and Smart Analytics for Industry 4.0 and Big Data Environment 1,861 citations
• The Effectiveness of Mobile-Health Technology-Based Health Behaviour Change or Disease Management Interventions for Health Care Consumers: A Systematic Review 1,860 citations
• Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values 1,860 citations
• Changing Epidemiology of Small-Cell Lung Cancer in the United States Over the Last 30 Years: Analysis of the Surveillance, Epidemiologic, and End Results Database 1,859 citations
• Cardiac-Resynchronization Therapy for Mild-to-Moderate Heart Failure 1,859 citations
• Interpreting Black-Box Models: A Review on Explainable Artificial Intelligence 1,859 citations
• Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions 1,858 citations
• Phenotypic and functional features of human Th17 cells 1,858 citations
• Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells 1,857 citations
• Development of a New Patient-Reported Outcome Measure for Breast Surgery: The BREAST-Q 1,857 citations
• A Core System for the Implementation of Task Sets 1,857 citations
• ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction 1,857 citations
• Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack 1,856 citations
• Erlotinib in Lung Cancer — Molecular and Clinical Predictors of Outcome 1,855 citations
• Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis 1,854 citations
• KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update 1,854 citations
• Virus-Enabled Synthesis and Assembly of Nanowires for Lithium Ion Battery Electrodes 1,853 citations
• 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death 1,853 citations
• Impact of the Metabolic Syndrome on Mortality From Coronary Heart Disease, Cardiovascular Disease, and All Causes in United States Adults 1,852 citations
• Soluble endoglin contributes to the pathogenesis of preeclampsia 1,852 citations
• Revising the definition of Alzheimer's disease: a new lexicon 1,852 citations
• Low-Dose CT With a Residual Encoder-Decoder Convolutional Neural Network 1,852 citations
• Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure 1,852 citations
• EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update 1,851 citations
• Atopic dermatitis 1,850 citations
• Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target 1,849 citations
• Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015 1,847 citations
• Cholesterol determination in high-density lipoproteins separated by three different methods. 1,846 citations
• Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells 1,845 citations
• Regression modelling strategies for improved prognostic prediction 1,845 citations
• KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD 1,845 citations
• Neurobehavioural effects of developmental toxicity 1,845 citations
• A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis 1,844 citations
• Subjective Burden of Husbands and Wives as Caregivers: A Longitudinal Study 1,844 citations
• ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications 1,843 citations
• DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs 1,842 citations
• Biochemical verification of tobacco use and cessation 1,842 citations
• Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing 1,841 citations
• Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample 1,841 citations
• Perovskite light-emitting diodes based on solution-processed self-organized multiple quantum wells 1,841 citations
• Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS) 1,840 citations
• 2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension 1,839 citations
• Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association 1,839 citations
• Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes 1,838 citations
• Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions 1,838 citations
• Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project 1,838 citations
• Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 1,838 citations
• Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation 1,836 citations
• Brain charts for the human lifespan 1,835 citations
• Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes 1,834 citations
• Transmission and spreading of tauopathy in transgenic mouse brain 1,834 citations
• Translating the A1C Assay Into Estimated Average Glucose Values 1,834 citations
• Vinorelbine plus Cisplatin vs. Observation in Resected Non–Small-Cell Lung Cancer 1,834 citations
• Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease 1,834 citations
• Stillbirths: rates, risk factors, and acceleration towards 2030 1,833 citations
• Transporting information and energy simultaneously 1,830 citations
• A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer 1,829 citations
• Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension 1,829 citations
• THE SEVENTH REPORT OF THE JOINT NATIONAL COMMITTEE ON PREVENTION, DETECTION, EVALUATION, AND TREATMENT OF HIGH BLOOD PRESSURE. THE JNC 7 REPORT 1,828 citations
• Constructing Experimental Designs for Discrete-Choice Experiments: Report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force 1,828 citations
• Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta 1,827 citations
• Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure 1,827 citations
• Status of Hypertension in China 1,827 citations
• Use of Colonoscopy to Screen Asymptomatic Adults for Colorectal Cancer 1,826 citations
• A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)? 1,826 citations
• Computing Interaction Effects and Standard Errors in Logit and Probit Models 1,825 citations
• Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus 1 with Zidovudine Treatment 1,825 citations
• Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64) 1,825 citations
• Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis 1,824 citations
• Left Ventricular Remodeling After Myocardial Infarction 1,822 citations
• Evidence that fibroblasts derive from epithelium during tissue fibrosis 1,822 citations
• Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients 1,822 citations
• Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial 1,822 citations
• Prevalence and determinants of common perinatal mental disorders in women in low- and lower-middle-income countries: a systematic review 1,821 citations
• A Clinical Trial Comparing Three Antithrombotic-Drug Regimens after Coronary-Artery Stenting 1,821 citations
• Entrainment of Neuronal Oscillations as a Mechanism of Attentional Selection 1,819 citations
• Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction 1,819 citations
• Recommendations for the extraction, analysis, and presentation of results in scoping reviews 1,819 citations
• Does Simulation-Based Medical Education With Deliberate Practice Yield Better Results Than Traditional Clinical Education? A Meta-Analytic Comparative Review of the Evidence 1,818 citations
• Design and Evaluation of Useful Bacterium-Specific PCR Primers That Amplify Genes Coding for Bacterial 16S rRNA 1,818 citations
• A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis 1,818 citations
• Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007-2008 1,817 citations
• EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD) 1,817 citations
• Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures 1,816 citations
• Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis 1,816 citations
• 2016 ESC Guidelines for the Management of Atrial Fibrillation Developed in Collaboration With EACTS 1,816 citations
• Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China 1,816 citations
• How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) 1,815 citations
• Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer 1,813 citations
• Early palliative care for patients with advanced cancer: a cluster-randomised controlled trial 1,812 citations
• The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes 1,812 citations
• Cells of the adult human heart 1,812 citations
• Increased rate of force development and neural drive of human skeletal muscle following resistance training 1,811 citations
• On the Regulation of the Blood‐supply of the Brain 1,810 citations
• Sotorasib for Lung Cancers with <i>KRAS</i> p.G12C Mutation 1,810 citations
• Canadian Network for Mood and Anxiety Treatments (<scp>CANMAT</scp>) and International Society for Bipolar Disorders (<scp>ISBD</scp>) 2018 guidelines for the management of patients with bipolar disorder 1,809 citations
• Lipoprotein(a) as a cardiovascular risk factor: current status 1,807 citations
• Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies 1,807 citations
• ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis 1,807 citations
• 2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease‐modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis 1,806 citations
• The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis 1,805 citations
• Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study 1,805 citations
• Regression modeling strategies : with applications to linear models, logistic and ordinal regression, and survival analysis 1,804 citations
• Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma 1,804 citations
• Industry 5.0: A survey on enabling technologies and potential applications 1,803 citations
• A minimal common outcome measure set for COVID-19 clinical research 1,802 citations
• Atopic dermatitis 1,802 citations
• Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis 1,801 citations
• Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine 1,799 citations
• Subclinical Thyroid Disease 1,798 citations
• Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma 1,797 citations
• Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis 1,796 citations
• A Randomized Trial of a Low-Carbohydrate Diet for Obesity 1,795 citations
• Wnt activity defines colon cancer stem cells and is regulated by the microenvironment 1,794 citations
• A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy 1,793 citations
• Proteogenomics connects somatic mutations to signalling in breast cancer 1,793 citations
• Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella 1,791 citations
• Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy 1,791 citations
• The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data 1,791 citations
• Systematic identification of trans eQTLs as putative drivers of known disease associations 1,789 citations
• Early infancy microbial and metabolic alterations affect risk of childhood asthma 1,789 citations
• Ulcerative Colitis and Colorectal Cancer 1,789 citations
• The PREMIER study: A multicenter, randomized, double‐blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment 1,788 citations
• Language control in bilinguals: The adaptive control hypothesis 1,788 citations
• Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial 1,788 citations
• Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension 1,787 citations
• Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine 1,786 citations
• Redefining the invertebrate RNA virosphere 1,785 citations
• Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis 1,783 citations
• Epidemiology of Diabetes and Diabetes-Related Complications 1,783 citations
• Battery, Ultracapacitor, Fuel Cell, and Hybrid Energy Storage Systems for Electric, Hybrid Electric, Fuel Cell, and Plug-In Hybrid Electric Vehicles: State of the Art 1,782 citations
• 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: Executive Summary 1,781 citations
• Hypocretin (orexin) deficiency in human narcolepsy 1,781 citations
• Inequality in early childhood: risk and protective factors for early child development 1,781 citations
• A Clinical Trial of the Angiotensin-Converting–Enzyme Inhibitor Trandolapril in Patients with Left Ventricular Dysfunction after Myocardial Infarction 1,781 citations
• Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank 1,781 citations
• COVID-19 illness in native and immunosuppressed states: A clinical–therapeutic staging proposal 1,781 citations
• Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma 1,781 citations
• Mental health literacy: Empowering the community to take action for better mental health. 1,780 citations
• Osimertinib in Resected <i>EGFR</i> -Mutated Non–Small-Cell Lung Cancer 1,780 citations
• Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure 1,779 citations
• Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis 1,779 citations
• Chronic Kidney Disease Diagnosis and Management 1,779 citations
• Resolving the fibrotic niche of human liver cirrhosis at single-cell level 1,779 citations
• Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias 1,778 citations
• Large recurrent microdeletions associated with schizophrenia 1,778 citations
• Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials 1,776 citations
• Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus 1,775 citations
• Contrasting Computational Models of Mate Preference Integration Across 45 Countries 1,775 citations
• Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency 1,774 citations
• Angiotensin-converting enzyme 2 is an essential regulator of heart function 1,773 citations
• Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma 1,773 citations
• Mediterranean diet pyramid today. Science and cultural updates 1,772 citations
• Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument. 1,771 citations
• Critical review: vegetables and fruit in the prevention of chronic diseases 1,770 citations
• Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease 1,770 citations
• Cardiac-Specific Troponin I Levels to Predict the Risk of Mortality in Patients with Acute Coronary Syndromes 1,770 citations
• Reporting standards for endovascular aortic aneurysm repair 1,769 citations
• The Inconsistency of “Optimal” Cutpoints Obtained using Two Criteria based on the Receiver Operating Characteristic Curve 1,769 citations
• Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement 1,769 citations
• The Importance of the Normality Assumption in Large Public Health Data Sets 1,769 citations
• A Randomized Trial of Exemestane after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer 1,768 citations
• Atopic Dermatitis 1,768 citations
• Stretchable active-matrix organic light-emitting diode display using printable elastic conductors 1,766 citations
• The Hinode (Solar-B) Mission: An Overview 1,766 citations
• International incidence of childhood cancer, 2001–10: a population-based registry study 1,766 citations
• Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology 1,766 citations
• AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update 1,765 citations
• Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis 1,764 citations
• Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records 1,761 citations
• Fighting COVID-19 Misinformation on Social Media: Experimental Evidence for a Scalable Accuracy-Nudge Intervention 1,761 citations
• Genotype-Phenotype Correlation in the Long-QT Syndrome 1,760 citations
• Orthogonal Time Frequency Space Modulation 1,760 citations
• Postmenopausal Osteoporosis 1,759 citations
• Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future 1,759 citations
• Grading quality of evidence and strength of recommendations for diagnostic tests and strategies 1,758 citations
• Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs 1,758 citations
• CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells 1,757 citations

Nothing on this page matches that.