Papers.

• The Clinical Diagnosis of Alzheimer's Disease 1,380 citations
• Systemic lupus erythematosus 1,380 citations
• 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents 1,380 citations
• Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction 1,379 citations
• EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis 1,379 citations
• OCEANS: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Chemotherapy With or Without Bevacizumab in Patients With Platinum-Sensitive Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer 1,379 citations
• PARIHS revisited: from heuristic to integrated framework for the successful implementation of knowledge into practice 1,379 citations
• 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5) 1,379 citations
• Designing and evaluating complex interventions to improve health care 1,378 citations
• Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort 1,378 citations
• Colorectal cancer screening: a global overview of existing programmes 1,378 citations
• Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection 1,378 citations
• Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes 1,377 citations
• Gene therapy comes of age 1,377 citations
• A Contemporary Prostate Cancer Grading System: A Validated Alternative to the Gleason Score 1,376 citations
• What Works for Whom?: A Critical Review of Psychotherapy Research 1,376 citations
• Incidence of Adenocarcinoma among Patients with Barrett's Esophagus 1,376 citations
• The capacity for understanding mental states: The reflective self in parent and child and its significance for security of attachment 1,376 citations
• The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study 1,376 citations
• Spiral of Cynicism 1,376 citations
• Neighborhood Socioeconomic Disadvantage and 30-Day Rehospitalization 1,375 citations
• DNA methylation age of blood predicts all-cause mortality in later life 1,375 citations
• Coupling of the nucleus and cytoplasm: Role of the LINC complex 1,375 citations
• Rate of force development: physiological and methodological considerations 1,375 citations
• Immune checkpoint inhibitors for patients with advanced lung cancer and oncogenic driver alterations: results from the IMMUNOTARGET registry 1,375 citations
• Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells 1,375 citations
• Damage Control Resuscitation: Directly Addressing the Early Coagulopathy of Trauma 1,374 citations
• Computer Therapy for the Anxiety and Depressive Disorders Is Effective, Acceptable and Practical Health Care: A Meta-Analysis 1,374 citations
• Root Signals and the Regulation of Growth and Development of Plants in Drying Soil 1,374 citations
• Long-Term Clinical Efficacy of Grass-Pollen Immunotherapy 1,374 citations
• Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease? 1,373 citations
• Thrombolysis for acute ischaemic stroke 1,373 citations
• Loneliness and Risk of Alzheimer Disease 1,373 citations
• Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials 1,373 citations
• Nitrogen and sulfur deposition on regional and global scales: A multimodel evaluation 1,373 citations
• The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013 1,373 citations
• Hypertrophic Cardiomyopathy 1,373 citations
• Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis 1,373 citations
• Explicit syllable and phoneme segmentation in the young child 1,372 citations
• Rituximab-CHOP Versus CHOP Alone or With Maintenance Rituximab in Older Patients With Diffuse Large B-Cell Lymphoma 1,372 citations
• Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial 1,372 citations
• Mechanisms of resistance to immune checkpoint inhibitors 1,372 citations
• Circadian Typology: A Comprehensive Review 1,371 citations
• Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies 1,371 citations
• Genetic progression model for head and neck cancer: implications for field cancerization. 1,370 citations
• Using multiple genetic variants as instrumental variables for modifiable risk factors 1,370 citations
• Utility of food-specific IgE concentrations in predicting symptomatic food allergy 1,370 citations
• Physical Measurements as Risk Indicators for Low-Back Trouble Over a One-Year Period 1,370 citations
• Deep Recurrent Neural Networks for Hyperspectral Image Classification 1,369 citations
• The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: Executive summary 1,368 citations
• EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy 1,368 citations
• Potential Biases in Machine Learning Algorithms Using Electronic Health Record Data 1,368 citations
• Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder 1,368 citations
• Attention-deficit/hyperactivity disorder 1,368 citations
• Heat-Related Deaths during the July 1995 Heat Wave in Chicago 1,367 citations
• A six-item short-form survey for measuring headache impact: The HIT-6™ 1,367 citations
• The Metabolic Syndrome and Chronic Kidney Disease in U.S. Adults 1,367 citations
• Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study 1,367 citations
• ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors 1,367 citations
• Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus 1,367 citations
• Aberrant CpG-island methylation has non-random and tumour-type–specific patterns 1,366 citations
• Reduction in Inappropriate Therapy and Mortality through ICD Programming 1,366 citations
• Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation 1,366 citations
• A Proportional Hazards Model for the Subdistribution of a Competing Risk 1,366 citations
• Ciliopathies 1,366 citations
• Seventh INTERMACS annual report: 15,000 patients and counting 1,365 citations
• Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases 1,365 citations
• European Respiratory Society guidelines for the management of adult bronchiectasis 1,365 citations
• ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary 1,364 citations
• Influence of social network on occurrence of dementia: a community-based longitudinal study 1,364 citations
• ESPEN Guidelines on Enteral Nutrition: Intensive care 1,364 citations
• A Randomized Trial of Maintenance Therapy for Vasculitis Associated with Antineutrophil Cytoplasmic Autoantibodies 1,363 citations
• A Rubberlike Stretchable Active Matrix Using Elastic Conductors 1,363 citations
• Phase III Trial of Trimodality Therapy With Cisplatin, Fluorouracil, Radiotherapy, and Surgery Compared With Surgery Alone for Esophageal Cancer: CALGB 9781 1,363 citations
• Chemotherapy Followed by Surgery Compared with Surgery Alone for Localized Esophageal Cancer 1,363 citations
• Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis 1,362 citations
• Human Temporal Lobe Activation by Speech and Nonspeech Sounds 1,362 citations
• Guard Cell Signal Transduction Network: Advances in Understanding Abscisic Acid, CO₂, and Ca²⁺Signaling 1,362 citations
• Innovation management measurement: A review 1,362 citations
• Annual High-Dose Oral Vitamin D and Falls and Fractures in Older Women 1,362 citations
• Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association 1,362 citations
• Colorectal cancer 1,362 citations
• Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. 1,361 citations
• Translation, Adaptation, and Validation of the SF-36 Health Survey for Use in Japan 1,361 citations
• HIV Infection and the Risk of Acute Myocardial Infarction 1,361 citations
• Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma 1,361 citations
• Combinations of muscle synergies in the construction of a natural motor behavior 1,360 citations
• Predicting Psychosis 1,360 citations
• The Braden Scale for Predicting Pressure Sore Risk 1,360 citations
• Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group 1,360 citations
• American Society of Hematology 2019 guidelines for immune thrombocytopenia 1,360 citations
• Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2) 1,360 citations
• Multimorbidity 1,360 citations
• Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia 1,359 citations
• Improved Survival in Metastatic Colorectal Cancer Is Associated With Adoption of Hepatic Resection and Improved Chemotherapy 1,359 citations
• 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study) 1,359 citations
• Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. 1,359 citations
• Antioxidants and Atherosclerotic Heart Disease 1,359 citations
• ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment 1,359 citations
• Effect of Weight Loss With Lifestyle Intervention on Risk of Diabetes 1,358 citations
• Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association 1,358 citations
• CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy 1,358 citations
• Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association 1,358 citations
• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 1,357 citations
• Characterization of Weighted Quantile Sum Regression for Highly Correlated Data in a Risk Analysis Setting 1,357 citations
• Broca's region revisited: Cytoarchitecture and intersubject variability 1,357 citations
• The CRIT Study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States* 1,357 citations
• Trial of Anifrolumab in Active Systemic Lupus Erythematosus 1,357 citations
• American College of Rheumatology classification criteria for Sjögren's syndrome: A data‐driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance Cohort 1,356 citations
• The Existence of Publication Bias and Risk Factors for Its Occurrence 1,356 citations
• Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial 1,356 citations
• Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram 1,356 citations
• Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors 1,355 citations
• Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial 1,355 citations
• Extending the Linear Model with R: Generalized Linear, Mixed Effects and Nonparametric Regression Models 1,354 citations
• Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis 1,354 citations
• Guidelines for Performing a Comprehensive Transesophageal Echocardiographic Examination: Recommendations from the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists 1,352 citations
• Effect of Carvedilol on the Morbidity of Patients With Severe Chronic Heart Failure 1,352 citations
• Food, youth and the Mediterranean diet in Spain. Development of KIDMED, Mediterranean Diet Quality Index in children and adolescents 1,351 citations
• INT 0123 (Radiation Therapy Oncology Group 94-05) Phase III Trial of Combined-Modality Therapy for Esophageal Cancer: High-Dose Versus Standard-Dose Radiation Therapy 1,351 citations
• Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents 1,351 citations
• Banff 2013 Meeting Report: Inclusion of C4d-Negative Antibody-Mediated Rejection and Antibody-Associated Arterial Lesions 1,350 citations
• A Review of Indocyanine Green Fluorescent Imaging in Surgery 1,350 citations
• Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 1,350 citations
• Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials 1,350 citations
• Riociguat for the Treatment of Pulmonary Arterial Hypertension 1,350 citations
• Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement 1,350 citations
• Helping Doctors and Patients Make Sense of Health Statistics 1,349 citations
• Sample Size Tables for Clinical Studies 1,348 citations
• Molecular Ordering of Organic Molten Salts Triggered by Single-Walled Carbon Nanotubes 1,348 citations
• The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution 1,348 citations
• Pallidal versus Subthalamic Deep-Brain Stimulation for Parkinson's Disease 1,348 citations
• Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer 1,348 citations
• The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013 1,347 citations
• Role of Physical Activity and Sedentary Behavior in the Mental Health of Preschoolers, Children and Adolescents: A Systematic Review and Meta-Analysis 1,347 citations
• Diabetes, Hypertension, and Cardiovascular Disease 1,346 citations
• Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update 1,346 citations
• Laparoscopic Nephrectomy: Initial Case Report 1,346 citations
• Complement and the damaging effects of cardiopulmonary bypass 1,346 citations
• Normal Vascular Aging: Differential Effects on Wave Reflection and Aortic Pulse Wave Velocity 1,345 citations
• Consensus statement on injury definitions and data collection procedures in studies of football (soccer) injuries 1,345 citations
• Regular physical exercise and low-fat diet. Effects on progression of coronary artery disease. 1,344 citations
• Defining clinically meaningful change in health-related quality of life 1,344 citations
• Preservation of Pancreatic β-Cell Function and Prevention of Type 2 Diabetes by Pharmacological Treatment of Insulin Resistance in High-Risk Hispanic Women 1,344 citations
• Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome 1,344 citations
• Regulation of drought tolerance by gene manipulation of 9‐<i>cis</i>‐epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in <i>Arabidopsis</i> 1,343 citations
• Increase in Circulating Products of Lipid Peroxidation (F₂-Isoprostanes) in Smokers — Smoking as a Cause of Oxidative Damage 1,343 citations
• Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19 1,343 citations
• Adverse Impact of Bleeding on Prognosis in Patients With Acute Coronary Syndromes 1,343 citations
• A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes 1,343 citations
• Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer 1,343 citations
• 2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline) 1,342 citations
• Evaluating the successful implementation of evidence into practice using the PARiHS framework: theoretical and practical challenges 1,342 citations
• Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. 1,342 citations
• Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis 1,342 citations
• Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. 1,341 citations
• Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis 1,341 citations
• The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling 1,341 citations
• Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria 1,341 citations
• Motor Competence and its Effect on Positive Developmental Trajectories of Health 1,340 citations
• A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions 1,340 citations
• The anatomy of language: contributions from functional neuroimaging 1,340 citations
• Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women 1,340 citations
• Deciphering cell–cell interactions and communication from gene expression 1,340 citations
• Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction 1,339 citations
• Protein kinase C activation and the development of diabetic complications. 1,339 citations
• A Trial of Intracranial-Pressure Monitoring in Traumatic Brain Injury 1,339 citations
• Catalytic in vivo protein knockdown by small-molecule PROTACs 1,338 citations
• Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment 1,338 citations
• Clinical Course of Breast Cancer Patients With Complete Pathologic Primary Tumor and Axillary Lymph Node Response to Doxorubicin-Based Neoadjuvant Chemotherapy 1,338 citations
• Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline 1,338 citations
• Small-Vessel Vasculitis 1,338 citations
• Long-Term Prognosis Associated With Coronary Calcification 1,337 citations
• Aortic Stenosis in the Elderly 1,337 citations
• Update on food allergy 1,337 citations
• Use of Positron Emission Tomography for Response Assessment of Lymphoma: Consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma 1,337 citations
• Effect of Exercise on Coronary Endothelial Function in Patients with Coronary Artery Disease 1,337 citations
• Statistical Methods for the Analysis of Discrete Choice Experiments: A Report of the ISPOR Conjoint Analysis Good Research Practices Task Force 1,336 citations
• Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution 1,336 citations
• Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial 1,336 citations
• A mechanism for impaired fear recognition after amygdala damage 1,335 citations
• A link between the systems: functional differentiation and integration within the human insula revealed by meta-analysis 1,335 citations
• A new rating scale for adult resilience: what are the central protective resources behind healthy adjustment? 1,335 citations
• Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network 1,335 citations
• Walking Compared with Vigorous Exercise for the Prevention of Cardiovascular Events in Women 1,334 citations
• Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis 1,334 citations
• Lipid A Modification Systems in Gram-Negative Bacteria 1,334 citations
• Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth 1,334 citations
• Combination Chemotherapy as an Adjuvant Treatment in Operable Breast Cancer 1,334 citations
• Safe prevention of the primary cesarean delivery 1,333 citations
• Early Intensive vs a Delayed Conservative Simvastatin Strategy in Patients With Acute Coronary Syndromes 1,333 citations
• The Efficacy of Surgical Modifications of the Upper Airway in Adults With Obstructive Sleep Apnea Syndrome 1,333 citations
• American Society of Clinical Oncology Provisional Clinical Opinion: The Integration of Palliative Care Into Standard Oncology Care 1,333 citations
• GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction 1,333 citations
• Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial 1,333 citations
• Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP 1,332 citations
• How Learning to Read Changes the Cortical Networks for Vision and Language 1,332 citations
• Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers 1,332 citations
• Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer 1,332 citations
• Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women 1,331 citations

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