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affect sleep in wild type laboratory mice.
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affect sleep in wild type laboratory mice. is a researcher indexed in ScholarIQ from OpenAlex & ORCID.
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affect sleep in wild type laboratory mice. has 1 works in the ScholarIQ index. The count is the OpenAlex total, not the number of papers listed on this page.
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affect sleep in wild type laboratory mice. has 3 citations in the OpenAlex counts ScholarIQ stores.
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affect sleep in wild type laboratory mice. has an h-index of 1 in OpenAlex.
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affect sleep in wild type laboratory mice. has an i10-index of 0 in OpenAlex.
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Oral Abstract
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are chemogenetic tools for remote control of targeted cell populations using chemical actuators that bind to modified receptors. Despite the popularity of DREADDs in neuroscience and sleep research, potential effects of clozapine-N-oxide (CNO) and other DREADD actuators on sleep have never been systematically tested. Recent reports suggest that CNO can affect brain activity and animal behaviour, putatively through conversion to clozapine. The aim of our study was to assess whether CNO or compound 21 (C21), a novel actuator that cannot convert to clozapine, affect sleep in wild type laboratory mice.