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Christine A. Pratilas
ResearcherPublications, citations & collaboration network
Christine A. Pratilas is a researcher indexed in ScholarIQ from OpenAlex & ORCID. ScholarIQ records 670 works, 8,734 citations, an h-index of 41 and an i10-index of 76.
670
Works
8,734
Citations
41
h-index
76
i10-index
How has Christine A. Pratilas's publication output changed over time?
ScholarIQpublication output · 2005–2025
Output grew0% over the shown period — from 1 works in 2005 to 1 in 2025.
1
1
1
3
2
1
1
1
20052008200920102012201420152025
What are the most-cited papers on Christine A. Pratilas?
ScholarIQmost cited works
BRAF mutation predicts sensitivity to MEK inhibition
David B. Solit, Levi A. Garraway, Christine A. Pratilas, Ayana Sawai, Gad Getz, Andrea Basso, Qing Ye, Jose Lobo, Yuhong She, Iman Osman, Todd R. Golub, Judith S. Sebolt–Leopold, William R. Sellers, Neal Rosen
Nature. 20051,330 CitationsOPEN ACCESS
<sup>V600E</sup> BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
Christine A. Pratilas, Barry S. Taylor, Qing Ye, Agnès Viale, Chris Sander, David B. Solit, Neal Rosen
Proceedings of the National Academy of Sciences. 2009617 CitationsOPEN ACCESS
Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
Piro Lito, Christine A. Pratilas, Eric W. Joseph, Madhavi Tadi, Ensar Halilovic, Matthew Zubrowski, Alan Huang, Wai Lin Wong, Margaret K. Callahan, Taha Merghoub, Jedd D. Wolchok, Elisa de Stanchina, Sarat Chandarlapaty, Poulikos I. Poulikakos, James A. Fagin, Neal Rosen
S25671836. 2012572 CitationsOPEN ACCESS
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
Eric W. Joseph, Christine A. Pratilas, Poulikos I. Poulikakos, Madhavi Tadi, Weiqing Wang, Barry S. Taylor, Ensar Halilovic, Yogindra Persaud, Feng Xing, Agnès Viale, James Tsai, Paul B. Chapman, Gideon Bollag, David B. Solit, Neal Rosen
Proceedings of the National Academy of Sciences. 2010448 CitationsOPEN ACCESS
Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence
Moriah H. Nissan, Christine A. Pratilas, Alexis M. Jones, Ricardo J. Ramirez, Helen Won, Cailian Liu, Shakuntala Tiwari, Li Ren Kong, Aphrothiti J. Hanrahan, Zhan Yao, Taha Merghoub, Antoni Ribas, Paul B. Chapman, Rona Yaeger, Barry S. Taylor, Nikolaus Schultz, Michael F. Berger, Neal Rosen, David B. Solit
Cancer Research. 2014312 CitationsOPEN ACCESS
Related on ScholarIQ
Johns Hopkins University
Institution
BRAF mutation predicts sensitivity to MEK inhibition
Paper
<sup>V600E</sup> BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway
Paper
Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
Paper
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
Paper
Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence
Paper