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Calpain Protease Function and Regulation
TopicLeading institutions, researchers & key papers
This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
24
Works
IDs:OpenAlex
How has Calpain Protease Function and Regulation's publication output changed over time?
ScholarIQpublication output · 1999–2010
Output grew0% over the shown period — from 1 works in 1999 to 1 in 2010.
1
1
1
1
1
1
1
1999200120032005200720082010
What are the most-cited papers on Calpain Protease Function and Regulation?
ScholarIQmost cited works
Meta-Analysis and a Large Association Study Confirm a Role for Calpain-10 Variation in Type 2 Diabetes Susceptibility
Michael N. Weedon, Peter E. H. Schwarz, Yukio Horikawa, Naoko Iwasaki, Thomas Illig, Rolf Holle, Wolfgang Rathmann, T. Selisko, Jan Schulze, Katherine R. Owen, Julie Evans, Laura del Bosque‐Plata, G. A. Hitman, Mark Walker, J Lévy, Mike Sampson, Graeme I. Bell, Mark I. McCarthy, Andrew T. Hattersley, Timothy M. Frayling
S134425043. 2003184 CitationsOPEN ACCESS
Calpastatin Is Up-regulated in Response to Hypoxia and Is a Suicide Substrate to Calpain after Neonatal Cerebral Hypoxia-Ischemia
Klas Blomgren, Ulrika Hallin, Anna-Lena Andersson, Małgorzata Puka‐Sundvall, Ben A. Bahr, Amanda McRae, Takaomi C. Saido, Seiichi Kawashima, Henrik Hagberg
S140251998. 1999113 CitationsOPEN ACCESS
Calpain 3 gene mutations: genetic and clinico-pathologic findings in limb-girdle muscular dystrophy
Jong‐Hee Chae, Narihiro Minami, Yuko Jin, Masahiro Nakagawa, Kumiko Murayama, Fumie Igarashi, Ikuya Nonaka
S50004817. 2001110 Citations
Genomic profiling of the neuronal target genes of the plasticity‐related transcription factor – Zif268
B. Allan, Allan B. James, AnnMarie AnnMarie, Conway, Jessica Brian, Mhairi A. Morris
S135837084. 200576 Citations
A Key Role for Calpains in Retinal Ganglion Cell Death
Declan P. McKernan, Marc Guérin, Colm O’Brien, Thomas G. Cotter
S76304953. 200762 Citations
Where is Calpain Protease Function and Regulation research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
S134425043184
S140251998113
S50004817110
S13583708476
S7630495362
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on Calpain Protease Function and Regulation is open access?
ScholarIQopen access share
43%OPEN ACCESS
Gold
0%
Green
14%
Hybrid
14%
Bronze
14%
Closed
57%
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