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Cancer, Hypoxia, and Metabolism
TopicLeading institutions, researchers & key papers
This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.
537
Works
IDs:OpenAlex
How has Cancer, Hypoxia, and Metabolism's publication output changed over time?
ScholarIQpublication output · 1999–2014
Output grew0% over the shown period — from 1 works in 1999 to 1 in 2014.
1
2
1
1
1
2
2
2
1
1
1999200020032004200520072011201220132014
What are the most-cited papers on Cancer, Hypoxia, and Metabolism?
ScholarIQmost cited works
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang, Steven C. Clifford, Emma C. Vaux, Matthew E. Cockman, Charles C. Wykoff, Christopher W. Pugh, Eamonn R. Maher, Peter J. Ratcliffe
Nature. 19995,219 Citations
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
Thorsten Cramer, Yuji Yamanishi, Björn E. Clausen, Irmgard Förster, Rafał Pawliński, Nigel Mackman, Volker H. Haase, Rudolf Jaenisch, Maripat Corr, Victor Nizet, Gary S. Firestein, Hans-Peter Gerber, Napoleone Ferrara, Randall S. Johnson
S110447773. 20032,034 CitationsOPEN ACCESS
Akt Stimulates Aerobic Glycolysis in Cancer Cells
Rebecca Elstrom, Daniel E. Bauer, Monica Buzzai, Robyn Karnauskas, Marian H. Harris, David R. Plas, Hongming Zhuang, Ryan M. Cinalli, Abass Alavi, Charles M. Rudin, Craig B. Thompson
Cancer Research. 20041,464 Citations
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Jason W. Locasale, Alexandra Grassian, Tamar Melman, Costas A. Lyssiotis, Katherine Mattaini, Adam J. Bass, Gregory J. Heffron, Christian M. Metallo, Taru Muranen, Hadar Sharfi, Atsuo T. Sasaki, Dimitrios Anastasiou, Edouard Mullarky, Natalie I. Vokes, Mika Sasaki, Rameen Beroukhim, Gregory Stephanopoulos, Azra H. Ligon, Matthew Meyerson, Andrea L. Richardson, Lynda Chin, Gerhard Wagner, John M. Asara, Joan S. Brugge, Lewis C. Cantley, Matthew G. Vander Heiden
S137905309. 20111,133 CitationsOPEN ACCESS
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
Anne Le, Andrew N. Lane, Max Hamaker, Sminu Bose, Arvin M. Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J. Rojas, Barbara S. Slusher, Haixia Zhang, Lisa J. Zimmerman, D.C. Liebler, Robbert J.C. Slebos, Pawel Lorkiewicz, Richard M. Higashi, Teresa W.‐M. Fan, Chi V. Dang
Cell Metabolism. 20121,098 CitationsOPEN ACCESS
Where is Cancer, Hypoxia, and Metabolism research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on Cancer, Hypoxia, and Metabolism is open access?
ScholarIQopen access share
67%OPEN ACCESS
Gold
0%
Green
7%
Hybrid
20%
Bronze
40%
Closed
33%
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