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Cancer Mechanisms and Therapy

TopicLeading institutions, researchers & key papers

Cancer Mechanisms and Therapy is a topic indexed in ScholarIQ from OpenAlex.

What is known about Cancer Mechanisms and Therapy?

ScholarIQrecord summary

This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.

How many works does Cancer Mechanisms and Therapy have?

ScholarIQindexed works

Cancer Mechanisms and Therapy has 179 works in the ScholarIQ index. The count is the OpenAlex total, not the number of papers listed on this page.

What is the OpenAlex record for Cancer Mechanisms and Therapy?

ScholarIQopenalex

The OpenAlex for Cancer Mechanisms and Therapy is on the source record.

What are the most-cited papers on Cancer Mechanisms and Therapy?

ScholarIQmost cited works
EGFR activation limits the response of liver cancer to lenvatinib
Haojie Jin, Yao Shi, Yuanyuan Lv, Shengxian Yuan, Christel Ramirez, Cor Lieftink, Liqin Wang, Siying Wang, Cun Wang, Matheus Henrique Dias, Fleur Jochems, Yuan Yang, Astrid Bosma, E. Marielle Hijmans, Marnix H. P. de Groot, Serena Vegna, Dan Cui, Yangyang Zhou, Ling Jing, Hui Wang, Yuchen Guo, Xingling Zheng, Nikita Isima, Hai-Qiu Wu, Chong Sun, Roderick L. Beijersbergen, Leila Akkari, Weiping Zhou, Bo Zhai, Wenxin Qin, René Bernards
Nature. 2021440 Citations
Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein
Kazuo Takahashi, Takuya Sasaki, Akiko Mammoto, Kenji Takaishi, Takaaki Kameyama, Sachiko Tsukita, Shöichiro Tsukita, Yoshimi Takai
Journal of Biological Chemistry. 1997429 CitationsOPEN ACCESS
Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma
Jian Huang, Qing Deng, Qun Wang, Kun Yu Li, Ji Hong Dai, Li Niu, Zhi Dong Zhu, Bo Zhou, Xiao Yan Liu, Rui Fang Liu, Qian Lan Fei, Hui Chen, Bing Cai, Boping Zhou, Hua-Sheng Xiao, Lun Qin, Ze‐Guang Han
Nature Genetics. 2012393 Citations
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations
Masao Mizuki, Joachim Schwäble, Claudia Steur, Chunaram Choudhary, Shuchi Agrawal, Bülent Sargin, Björn Steffen, Itaru Matsumura, Yuzuru Kanakura, Frank D. Böhmer, Carsten Müller‐Tidow, Wolfgang E. Berdel, Hubert Serve
Blood. 2003298 CitationsOPEN ACCESS
LINC01638 lncRNA activates MTDH-Twist1 signaling by preventing SPOP-mediated c-Myc degradation in triple-negative breast cancer
Liyun Luo, Hailin Tang, Ling Li, Nan Li, Xiaoting Jia, Zhijie Zhang, Xiaorong Wang, Lejuan Shi, Jiang Yin, Ni Qiu, Hao Liu, Ying Song, Kai Luo, Hongsheng Li, Zhimin He, Guopei Zheng, Xiaoming Xie
Oncogene. 2018151 Citations

Where is Cancer Mechanisms and Therapy research published, and who funds it?

ScholarIQvenues & funding sources

TOP FUNDERS

National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock

How much of the research on Cancer Mechanisms and Therapy is open access?

ScholarIQopen access share
47%OPEN ACCESS
Gold
13%
Green
7%
Hybrid
20%
Bronze
7%
Closed
53%

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