Complement system in diseases

TopicLeading institutions, researchers & key papers

This cluster of papers explores the role of the complement system in immune response, focusing on its involvement in thrombotic microangiopathies, hemolytic uremic syndrome, and inflammatory diseases. It delves into the genetics, regulation, and therapeutic interventions such as Eculizumab for managing complement-related disorders.

317

Works

IDs:OpenAlex

How has Complement system in diseases's publication output changed over time?

ScholarIQpublication output · 1993–2017

Output grew100% over the shown period — from 1 works in 1993 to 2 in 2017.

1993200620092010201120132014201520162017

What are the most-cited papers on Complement system in diseases?

ScholarIQmost cited works

Complement regulators and inhibitory proteins

Peter F. Zipfel, Christine Skerka

S93373720. 20091,272 Citations

Syndromes of Thrombotic Microangiopathy

James N. George, Carla Nester

New England Journal of Medicine. 20141,260 Citations

Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria

Junji Takeda, Toshio Miyata, Kazuyoshi Kawagoe, Yoshiyasu Iida, Yuichi Endo, Teizo Fujita, Minoru Takahashi, Teruo Kitani, Taroh Kinoshita

S110447773. 19931,049 Citations

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin, Chiara Mossali, Gaia Pianetti, Sara Gamba, Erica Daina, Chiara Fenili, Federica Castelletti, Annalisa Sorosina, Rossella Piras, Roberta Donadelli, Ramona Maranta, Irene van der Meer, Edward M. Conway, Peter F. Zipfel, Timothy H.J. Goodship, Giuseppe Remuzzi

Clinical Journal of the American Society of Nephrology. 20101,041 CitationsOPEN ACCESS

Guidelines on the Use of Therapeutic Apheresis in Clinical Practice–Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue

Joseph E. Schwartz, Anand Padmanabhan, Nicole A. Aqui, Rasheed A. Balogun, Laura Connelly‐Smith, Meghan Delaney, Nancy M. Dunbar, Volker Witt, Yanyun Wu, Beth H. Shaz

S189671064. 2016792 Citations