CRISPR and Genetic Engineering

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the use of CRISPR-Cas systems for genome engineering, RNA-guided gene editing, and bacterial immunity. It covers topics such as Cas9 nucleases, off-target effects, multiplex genome editing, and genetic screening using CRISPR technology.

274

Works

IDs:OpenAlex

How has CRISPR and Genetic Engineering's publication output changed over time?

ScholarIQpublication output · 2000–2020

Output grew100% over the shown period — from 1 works in 2000 to 2 in 2020.

200020072011201220132014201820192020

What are the most-cited papers on CRISPR and Genetic Engineering?

ScholarIQmost cited works

Global quantification of mammalian gene expression control

Björn Schwanhäußer, Dorothea Busse, Na Li, Gunnar Dittmar, Johannes Schuchhardt, Jana Wolf, Wei Chen, Matthias Selbach

Nature. 20116,967 Citations

A global double‐fluorescent Cre reporter mouse

Mandar D. Muzumdar, Bosiljka Tasic, Kazunari Miyamichi, Ling Li, Liqun Luo

S124648948. 20073,708 CitationsOPEN ACCESS

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen, Matthew Liebers, Ved V. Topkar, Vishal Thapar, Nicolas Wyvekens, Cyd Khayter, A. John Iafrate, Long P. Le, Martin J. Aryee, J. Keith Joung

S106963461. 20142,354 CitationsOPEN ACCESS

Gene therapy comes of age

Cynthia E. Dunbar, Katherine A. High, J. Keith Joung, Donald B. Kohn, Keiya Ozawa, Michel Sadelain

Science. 20181,377 Citations

In vivo genome editing using a high-efficiency TALEN system

Victoria M. Bedell, Ying Wang, Jarryd M. Campbell, Tanya L. Poshusta, Colby G. Starker, Randall G. Krug, Wenfang Tan, Sumedha G. Penheiter, C. H. Alvin, Anskar Y.H. Leung, Scott C. Fahrenkrug, Daniel F. Carlson, Daniel F. Voytas, Karl J. Clark, Jeffrey J. Essner, Stephen C. Ekker

Nature. 2012925 CitationsOPEN ACCESS