DNA Repair Mechanisms

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the molecular mechanisms of the DNA damage response, including DNA repair pathways, genomic instability, the role of ATM and ATR kinases, homologous recombination, cell cycle checkpoints, and their implications in cancer biology. It also explores the involvement of histone H2AX and chromatin in maintaining genome stability.

252

Works

IDs:OpenAlex

How has DNA Repair Mechanisms's publication output changed over time?

ScholarIQpublication output · 1995–2018

Output grew100% over the shown period — from 1 works in 1995 to 2 in 2018.

1995200020022004200520082010201320142018

What are the most-cited papers on DNA Repair Mechanisms?

ScholarIQmost cited works

DNA repair pathways as targets for cancer therapy

Thomas Helleday, Eva Petermann, Cecilia Lundin, Ben Hodgson, Ricky A. Sharma

S160464432. 20081,682 Citations

γH2AX and cancer

William M. Bonner, Christophe E. Redon, Jennifer S. Dickey, Asako Nakamura, Olga A. Sedelnikova, Stéphanie Solier, Yves Pommier

S160464432. 20081,611 CitationsOPEN ACCESS

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

Theo Knijnenburg, Linghua Wang, Michael T. Zimmermann, Nyasha Chambwe, Galen F. Gao, Andrew D. Cherniack, Huihui Fan, Hui Shen, Gregory P. Way, Casey S. Greene, Yuexin Liu, Rehan Akbani, Bin Feng, Lawrence A. Donehower, Chase Miller, Yang Shen, Mostafa Karimi, Hao Chen, Pora Kim, Peilin Jia, Eve Shinbrot, Shaojun Zhang, Jianfang Liu, Hai Hu, Matthew H. Bailey, Christina Yau, Denise M. Wolf, Zhongming Zhao, John N. Weinstein, Lei Li, Li Ding, Gordon B. Mills, Peter W. Laird, David A. Wheeler, Ilya Shmulevich, Rory Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy Defreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Jaegil Kim, Michael S. Lawrence, Pei Lin, Sam Meier, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila M. Reynolds, Ilya Shmulevich, Vésteinn Thórsson, Wei Zhang, Rehan Akbani, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi, Anil Korkut, Jun Li, Han Liang, Shiyun Ling, Wenbin Liu, Yiling Lu, Gordon B. Mills, Kwok-Shing Ng, Arvind Rao, Michael Ryan, Jing Wang, John N. Weinstein, Jiexin Zhang, Adam Abeshouse

S169236886. 20181,245 CitationsOPEN ACCESS

Polymorphisms in DNA repair genes and associations with cancer risk.

Ellen L. Goode, Cornelia M. Ulrich, John D. Potter

PubMed. 20021,204 Citations

<i>ATR</i> disruption leads to chromosomal fragmentation and early embryonic lethality

Eric J. Brown, David Baltimore

S168778273. 2000948 CitationsOPEN ACCESS