Hedgehog Signaling Pathway Studies

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the role of Hedgehog signaling in both animal development and cancer, particularly its involvement in tumorigenesis, stem cell renewal, and the progression of specific cancers such as pancreatic cancer and basal cell carcinoma. The papers also discuss the mechanisms of Hedgehog pathway inhibition and its potential as a therapeutic target for cancer treatment.

139

Works

IDs:OpenAlex

How has Hedgehog Signaling Pathway Studies's publication output changed over time?

ScholarIQpublication output · 2006–2021

Output grew0% over the shown period — from 1 works in 2006 to 1 in 2021.

2006200720082011201220132015201720192021

What are the most-cited papers on Hedgehog Signaling Pathway Studies?

ScholarIQmost cited works

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in <i>NOTCH1</i>

Nishant Agrawal, Mitchell J. Frederick, Curtis R. Pickering, Chetan Bettegowda, Kyle Chang, Ryan J. Li, Carole Fakhry, Tong-Xin Xie, Jiexin Zhang, Jing Wang, Nianxiang Zhang, Adel K. El‐Naggar, Samar A. Jasser, John N. Weinstein, Lisa R. Treviño, Jennifer Drummond, Donna M. Muzny, Yuanqing Wu, Laura D. Wood, Ralph H. Hruban, William H. Westra, Wayne M. Koch, Joseph A. Califano, Richard A. Gibbs, David Sidransky, Bert Vogelstein, Victor E. Velculescu, Nickolas Papadopoulos, David A. Wheeler, Kenneth W. Kinzler, Jeffrey N. Myers

Science. 20111,701 Citations

Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma

Aleksandar Sekulić, Michael R. Migden, Anthony E. Oro, Luc Dirix, Karl D. Lewis, John D. Hainsworth, James Solomon, Simon Yoo, Sarah T. Arron, Philip Friedlander, Ellen S. Marmur, Charles M. Rudin, Anne Lynn S. Chang, Jennifer A. Low, Howard Mackey, Robert L. Yauch, Richard Graham, Josina C. Reddy, Axel Hauschild

New England Journal of Medicine. 20121,452 CitationsOPEN ACCESS

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

David M. Berman, Sunil Karhadkar, Anirban Maitra, Rocío Montes de, Meg R. Gerstenblith, Kimberly J. Briggs, Antony R. Parker, Yutaka Shimada, James R. Eshleman, D. Neil Watkins, Philip A. Beachy

Nature. 20031,255 Citations

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells

Sara Piccirillo, Brent A. Reynolds, Nadia Zanetti, Giuseppe Lamorte, Elena Binda, Giovanni Broggi, Henry Brem, Alessandro Olivi, Francesco DiMeco, Angelo L. Vescovi

Nature. 20061,171 Citations

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

Christopher J. Ward, Marie C. Hogan, Sandro Rossetti, Denise L. Walker, Tam P. Sneddon, Xiaofang Wang, Vicky Kubly, Julie M. Cunningham, Robert L. Bacallao, Masahiko Ishibashi, Dawn S. Milliner, Vicente E. Torres, Peter C. Harris

S137905309. 2002765 Citations