Signaling Pathways in Disease

TopicLeading institutions, researchers & key papers

This cluster of papers focuses on the role of Calcineurin-NFAT signaling in transcriptional regulation, with a particular emphasis on its involvement in cancer progression, cardiac hypertrophy, and inflammatory responses. The cluster also explores the impact of Prolyl Isomerase Pin1, EMMPRIN/CD147, and immunophilins in modulating this signaling pathway.

129

Works

IDs:OpenAlex

How has Signaling Pathways in Disease's publication output changed over time?

ScholarIQpublication output · 1995–2020

Output grew0% over the shown period — from 2 works in 1995 to 2 in 2020.

1995199819992004200520062007201220182020

What are the most-cited papers on Signaling Pathways in Disease?

ScholarIQmost cited works

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Takashi Nakagawa, Shigeomi Shimizu, Tetsuya Watanabe, Osamu Yamaguchi, Kinya Otsu, Hirotaka Yamagata, Hidenori Inohara, Takeshi Kubo, Yoshihide Tsujimoto

Nature. 20051,616 Citations

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Ke Wang, Wei Chen, Zheng Zhang, Yong‐Qiang Deng, Jianqi Lian, Peng Du, Wei Ding, Zhang Yang, Xiuxuan Sun, Li Gong, Xu Yang, Lei He, Lei Zhang, Zhiwei Yang, Jiejie Geng, Ruo Chen, Hai Zhang, Bin Wang, Yumeng Zhu, Gang Nan, Jian‐Li Jiang, Ling Li, Jiao Wu, Peng Lin, Wan Huang, Liangzhi Xie, Zhaohui Zheng, Kui Zhang, Jinlin Miao, Hong‐Yong Cui, Min Huang, Jun Zhang, Ling Fu, Xiang-Min Yang, Zhongpeng Zhao, Shihui Sun, Hongjing Gu, Zhe Wang, Chunfu Wang, Ya-Cheng Lu, Yingying Liu, Qingyi Wang, Huijie Bian, Ping Zhu, Zhi‐Nan Chen

Signal Transduction and Targeted Therapy. 20201,216 CitationsOPEN ACCESS

Control of p70 S6 kinase by kinase activity of FRAP in vivo

Eric J. Brown, Peter A. Beal, Curtis T. Keith, Jie Chen, Tae Bum Shin, Stuart L. Schreiber

Nature. 1995717 Citations

SARS-CoV-2 invades host cells via a novel route: CD147-spike protein

Ke Wang, Wei Chen, Yusen Zhou, Jianqi Lian, Zheng Zhang, Peng Du, Li Gong, Yang Zhang, Hong‐Yong Cui, Jiejie Geng, Bin Wang, Xiuxuan Sun, Chunfu Wang, Xu Yang, Peng Lin, Yong‐Qiang Deng, Wei Ding, Xiangmin Yang, Yumeng Zhu, Kui Zhang, Zhaohui Zheng, Jinlin Miao, Ting Guo, Ying Shi, Jun Zhang, Ling Fu, Qingyi Wang, Huijie Bian, Ping Zhu, Zhi‐Nan Chen

bioRxiv (Cold Spring Harbor Laboratory). 2020694 CitationsOPEN ACCESS

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.

Jie Chen, Xiao-Feng Zheng, Eric J. Brown, S.L. Schreiber

Proceedings of the National Academy of Sciences. 1995572 CitationsOPEN ACCESS