ScholarIQanswers from OpenAlex
Synthesis and Biological Activity
TopicLeading institutions, researchers & key papers
Synthesis and Biological Activity is a topic indexed in ScholarIQ from OpenAlex.
What is known about Synthesis and Biological Activity?
ScholarIQrecord summary
This cluster of papers focuses on the chemistry, biology, and synthesis of antitumor antibiotics, particularly tetrahydroisoquinoline compounds such as Ecteinascidin. It covers topics such as total synthesis, marine-derived compounds, asymmetric synthesis, and DNA binding mechanisms. The research also explores the pharmacological activities and potential clinical utility of these compounds.
How many works does Synthesis and Biological Activity have?
ScholarIQindexed works
Synthesis and Biological Activity has 20 works in the ScholarIQ index. The count is the OpenAlex total, not the number of papers listed on this page.
What is the OpenAlex record for Synthesis and Biological Activity?
ScholarIQopenalex
The OpenAlex for Synthesis and Biological Activity is on the source record.
What are the most-cited papers on Synthesis and Biological Activity?
ScholarIQmost cited works
Phase I and Pharmacokinetic Study of Ecteinascidin-743, a New Marine Compound, Administered as a 24-hour Continuous Infusion in Patients With Solid Tumors
A. Taamma, J. L. Misset, M. Riofrio, C. Guzmán, Étienne Brain, Luis López Lázaro, Hilde Rosing, José Jimeno, Esteban Cvitkovic
Yondelis® (trabectedin, ET-743): the development of an anticancer agent of marine origin
Ch. van Kesteren, M. M. M. de Vooght, Luis López Lázaro, Ron A. A. Mathôt, Jan H.M. Schellens, José Jimeno, Jos H. Beijnen
A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies.
Miguel A. Villalona‐Calero, S. Gail Eckhardt, Geoffrey R. Weiss, Manuel Hidalgo, Jos H. Beijnen, Charlotte van Kesteren, Hilde Rosing, Elizabeth Campbell, Maura A. Kraynak, Luis López Lázaro, Cecilia Guzmán, Daniel D. Von Hoff, José Jimeno, Eric K. Rowinsky
Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study.
Charlotte van Kesteren, Esteban Cvitkovic, A. Taamma, Luis López Lázaro, José Jimeno, C. Guzmán, R A Math t, Jan H.M. Schellens, J.L. Misset, E. Brain, M.J.X Hillebrand, Hilde Rosing, Jos H. Beijnen
Antiproliferative and Apoptotic Activities of Linear Furocoumarins from<i>Notopterygium incisum</i>on Cancer Cell Lines
Shi‐Biao Wu, Fei Pang, Ying Wen, Hongfeng Zhang, Zheng Zhao, Jin‐Feng Hu
Where is Synthesis and Biological Activity research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
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How much of the research on Synthesis and Biological Activity is open access?
ScholarIQopen access share
14%OPEN ACCESS