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TGF-β signaling in diseases

TopicLeading institutions, researchers & key papers

TGF-β signaling in diseases is a topic indexed in ScholarIQ from OpenAlex.

What is known about TGF-β signaling in diseases?

ScholarIQrecord summary

This cluster of papers explores the diverse aspects of the Transforming Growth Factor Beta (TGF-ß) signaling pathway, including its role in Smad-dependent and Smad-independent pathways, tumor suppression, cancer progression, bone morphogenetic protein (BMP) signaling, immune response modulation, cell differentiation, metastasis, regulation of epithelial-mesenchymal transition (EMT), and angiogenesis. It also discusses the development and use of TGF-ß inhibitors for potential therapeutic interventions.

How many works does TGF-β signaling in diseases have?

ScholarIQindexed works

TGF-β signaling in diseases has 155 works in the ScholarIQ index. The count is the OpenAlex total, not the number of papers listed on this page.

What is the OpenAlex record for TGF-β signaling in diseases?

ScholarIQopenalex

The OpenAlex for TGF-β signaling in diseases is on the source record.

What are the most-cited papers on TGF-β signaling in diseases?

ScholarIQmost cited works
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
Hidetoshi Hayashi, Shirin Abdollah, Yubin Qiu, Jiexing Cai, YongYao Xu, Brian W. Grinnell, Mark A. Richardson, James N. Topper, Michael A. Gimbrone, Jeffrey L. Wrana, Dean Falb
Cell. 19971,341 CitationsOPEN ACCESS
Targeting the TGFβ pathway for cancer therapy
Cindy Neuzillet, Annemilaï Tijeras‐Raballand, Romain Cohen, Jérôme Cros, Sandrine Faivre, Éric Raymond, Armand de Gramont
Pharmacology & Therapeutics. 2014620 CitationsOPEN ACCESS
TGF-β and fibrosis in different organs — molecular pathway imprints
Dirk Pohlers, Julia Brenmoehl, Ivonne Löffler, Cornelia K. Müller, Carola Leipner, Stefan Schultze–Mosgau, Andreas Stallmach, Raimund W. Kinne, Günter Wolf
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2009581 CitationsOPEN ACCESS
TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling
Shirin Abdollah, Marina Macías‐Silva, Tomoo Tsukazaki, Hidetoshi Hayashi, Liliana Attisano, Jeffrey L. Wrana
Journal of Biological Chemistry. 1997481 CitationsOPEN ACCESS
Transcriptional control of osteoblast growth and differentiation
Gary S. Stein, Jane B. Lian, Janet L. Stein, André J. van Wijnen, Martı́n Montecino
Physiological Reviews. 1996440 Citations

Where is TGF-β signaling in diseases research published, and who funds it?

ScholarIQvenues & funding sources

TOP FUNDERS

National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock

How much of the research on TGF-β signaling in diseases is open access?

ScholarIQopen access share
80%OPEN ACCESS
Gold
7%
Green
7%
Hybrid
20%
Bronze
47%
Closed
20%

Related on ScholarIQ

The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
Paper
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
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Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Paper
Treatment of Acromegaly with the Growth Hormone–Receptor Antagonist Pegvisomant
Paper
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
Paper
Targeting the TGFβ pathway for cancer therapy
Paper
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