Upload Records Snowball Search Search OpenAlex
About the database ScholarIQanswers from OpenAlex
TGF-β signaling in diseases
TopicLeading institutions, researchers & key papers
This cluster of papers explores the diverse aspects of the Transforming Growth Factor Beta (TGF-ß) signaling pathway, including its role in Smad-dependent and Smad-independent pathways, tumor suppression, cancer progression, bone morphogenetic protein (BMP) signaling, immune response modulation, cell differentiation, metastasis, regulation of epithelial-mesenchymal transition (EMT), and angiogenesis. It also discusses the development and use of TGF-ß inhibitors for potential therapeutic interventions.
155
Works
IDs:OpenAlex
How has TGF-β signaling in diseases's publication output changed over time?
ScholarIQpublication output · 1997–2020
Output declined50% over the shown period — from 2 works in 1997 to 1 in 2020.
2
1
1
2
1
1
1
1
1
1
1997199920052009201220142015201720192020
What are the most-cited papers on TGF-β signaling in diseases?
ScholarIQmost cited works
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
Hidetoshi Hayashi, Shirin Abdollah, Yubin Qiu, Jiexing Cai, YongYao Xu, Brian W. Grinnell, Mark A. Richardson, James N. Topper, Michael A. Gimbrone, Jeffrey L. Wrana, Dean Falb
S110447773. 19971,341 CitationsOPEN ACCESS
Targeting the TGFβ pathway for cancer therapy
Cindy Neuzillet, Annemilaï Tijeras‐Raballand, Romain Cohen, Jérôme Cros, Sandrine Faivre, Éric Raymond, Armand de Gramont
Pharmacology & Therapeutics. 2014620 CitationsOPEN ACCESS
TGF-β and fibrosis in different organs — molecular pathway imprints
Dirk Pohlers, Julia Brenmoehl, Ivonne Löffler, Cornelia K. Müller, Carola Leipner, Stefan Schultze–Mosgau, Andreas Stallmach, Raimund W. Kinne, Günter Wolf
S4210173099. 2009581 CitationsOPEN ACCESS
TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling
Shirin Abdollah, Marina Macías‐Silva, Tomoo Tsukazaki, Hidetoshi Hayashi, Liliana Attisano, Jeffrey L. Wrana
S140251998. 1997481 CitationsOPEN ACCESS
Transcriptional control of osteoblast growth and differentiation
Gary S. Stein, Jane B. Lian, Janet L. Stein, André J. van Wijnen, Martı́n Montecino
S203035050. 1996440 Citations
Where is TGF-β signaling in diseases research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on TGF-β signaling in diseases is open access?
ScholarIQopen access share
80%OPEN ACCESS
Gold
7%
Green
7%
Hybrid
20%
Bronze
47%
Closed
20%
Related on ScholarIQ
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
Paper
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
Paper
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
Paper
Treatment of Acromegaly with the Growth Hormone–Receptor Antagonist Pegvisomant
Paper
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
Paper
Targeting the TGFβ pathway for cancer therapy
Paper