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Ubiquitin and proteasome pathways
TopicLeading institutions, researchers & key papers
This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation.
266
Works
IDs:OpenAlex
How has Ubiquitin and proteasome pathways's publication output changed over time?
ScholarIQpublication output · 1999–2020
Output grew100% over the shown period — from 1 works in 1999 to 2 in 2020.
1
1
1
1
2
1
2
1
1
2
1999200120032006200720102011201620182020
What are the most-cited papers on Ubiquitin and proteasome pathways?
ScholarIQmost cited works
The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro
Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero, Chia‐Yu Chu, Stephen J. Elledge, J. Wade Harper
S168778273. 1999950 CitationsOPEN ACCESS
How the ubiquitin–proteasome system controls transcription
Masafumi Muratani, William P. Tansey
S196724125. 2003805 Citations
The role of ubiquitination in tumorigenesis and targeted drug discovery
Lu Deng, Tong Meng, Lei Chen, Wenyi Wei, Ping Wang
Signal Transduction and Targeted Therapy. 2020780 CitationsOPEN ACCESS
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S. Maser, Bo Zhai, Lixin Wan, Alejandro Gutiérrez, Alan W. Lau, Yonghong Xiao, Amanda L. Christie, Jon C. Aster, Jeffrey Settleman, Steven P. Gygi, Andrew L. Kung, Thomas Look, Keiichi I. Nakayama, Ronald A. DePinho, Wenyi Wei
Nature. 2011634 CitationsOPEN ACCESS
Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer
Erik Kupperman, Edmund C. Lee, Yueying Cao, Bret Bannerman, Michael Fitzgerald, Allison Berger, Jie Yu, Yang Yu, Paul Hales, Frank J. Bruzzese, Jane Liu, Jonathan L. Blank, Khristofer Garcia, Christopher Tsu, Larry Dick, Paul Fleming, Li Yu, Mark Manfredi, Mark Rolfe, Joe Bolen
Cancer Research. 2010496 Citations
Where is Ubiquitin and proteasome pathways research published, and who funds it?
ScholarIQvenues & funding sources
TOP JOURNALS
TOP FUNDERS
National Science Foundation—
NIH—
Wellcome Trust—
European Research Council—
Funder breakdown is a member featureSign up free to unlock
How much of the research on Ubiquitin and proteasome pathways is open access?
ScholarIQopen access share
53%OPEN ACCESS
Gold
20%
Green
7%
Hybrid
0%
Bronze
27%
Closed
47%
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