Papers.

• Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1 1,503 citations
• Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults 1,503 citations
• Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 1,503 citations
• Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer 1,502 citations
• Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province 1,502 citations
• 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes 1,502 citations
• Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores 1,501 citations
• The Effect of Bisoprolol on Perioperative Mortality and Myocardial Infarction in High-Risk Patients Undergoing Vascular Surgery 1,501 citations
• Genome-wide association study identifies 74 loci associated with educational attainment 1,501 citations
• Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma 1,501 citations
• Physician Staffing Patterns and Clinical Outcomes in Critically Ill Patients 1,500 citations
• <i>Planck</i>2013 results. I. Overview of products and scientific results 1,500 citations
• Rosuvastatin in Older Patients with Systolic Heart Failure 1,500 citations
• Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014 1,499 citations
• TRIBUTE: A Phase III Trial of Erlotinib Hydrochloride (OSI-774) Combined With Carboplatin and Paclitaxel Chemotherapy in Advanced Non–Small-Cell Lung Cancer 1,499 citations
• Cell Biology of the Glomerular Podocyte 1,499 citations
• Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6) 1,499 citations
• Atopic dermatitis 1,499 citations
• Multiscale 3D Genome Rewiring during Mouse Neural Development 1,498 citations
• Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB–IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial 1,498 citations
• MULTIMODAL REPRESENTATION OF SPACE IN THE POSTERIOR PARIETAL CORTEX AND ITS USE IN PLANNING MOVEMENTS 1,497 citations
• Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2 1,496 citations
• The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management 1,496 citations
• RETRACTED: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 1,496 citations
• Dorsal and Ventral Attention Systems 1,495 citations
• Consensus Guidelines for the Management of Postoperative Nausea and Vomiting 1,495 citations
• Hyponatremia and Mortality among Patients on the Liver-Transplant Waiting List 1,495 citations
• Physical Activity for Cognitive and Mental Health in Youth: A Systematic Review of Mechanisms 1,495 citations
• Behavioral and Emotional Disorders in Children during the COVID-19 Epidemic 1,495 citations
• Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose 1,494 citations
• Truncations of Titin Causing Dilated Cardiomyopathy 1,494 citations
• Internet of Things in the 5G Era: Enablers, Architecture, and Business Models 1,494 citations
• Human primary liver cancer–derived organoid cultures for disease modeling and drug screening 1,494 citations
• Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients 1,493 citations
• Cognitive self-statements in depression: Development of an automatic thoughts questionnaire 1,493 citations
• Impact of Hemorrhage on Trauma Outcome: An Overview of Epidemiology, Clinical Presentations, and Therapeutic Considerations 1,492 citations
• Sleep Apnea and Cardiovascular Disease 1,491 citations
• Susceptibility to misinformation about COVID-19 around the world 1,491 citations
• Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials. 1,490 citations
• Pediatric modification of the Montreal classification for inflammatory bowel disease 1,490 citations
• Changes in the global burden of depression from 1990 to 2017: Findings from the Global Burden of Disease study 1,490 citations
• Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis 1,489 citations
• Measurement of Blood Pressure in Humans: A Scientific Statement From the American Heart Association 1,489 citations
• Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex 1,488 citations
• Peptic ulcer disease 1,488 citations
• Childhood Maltreatment Predicts Unfavorable Course of Illness and Treatment Outcome in Depression: A Meta-Analysis 1,488 citations
• Chlorhexidine–Alcohol versus Povidone–Iodine for Surgical-Site Antisepsis 1,488 citations
• American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis 1,487 citations
• Enteral Nutrient Supply for Preterm Infants: Commentary From the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition 1,487 citations
• Runs of Homozygosity in European Populations 1,487 citations
• Voxel-based lesion–symptom mapping 1,487 citations
• Physical, psychological and occupational consequences of job burnout: A systematic review of prospective studies 1,487 citations
• Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update 1,487 citations
• Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions 1,486 citations
• The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material 1,485 citations
• A New Definition of Children With Special Health Care Needs 1,484 citations
• Observation of Top Quark Production in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mrow><mml:mover><mml:mrow><mml:mi mathvariant="italic">p</mml:mi></mml:mrow><mml:mrow><mml:mi>¯</mml:mi></mml:mrow></mml:mover></mml:mrow></mml:mrow><mml:mi mathvariant="italic">p</mml:mi></mml:math>Collisions with the Collider Detector at Fermilab 1,483 citations
• The oscillating brain: Complex and reliable 1,483 citations
• Five-Year Outcomes of a Randomized Phase III Trial Comparing Adjuvant Chemotherapy With S-1 Versus Surgery Alone in Stage II or III Gastric Cancer 1,483 citations
• Diagnostic Performance of Noninvasive Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography in Suspected Coronary Artery Disease 1,483 citations
• Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation 1,483 citations
• Phthalates: Toxicology and exposure 1,482 citations
• Epithelial ovarian cancer: Evolution of management in the era of precision medicine 1,482 citations
• Total Antioxidant Capacity of Plant Foods, Beverages and Oils Consumed in Italy Assessed by Three Different In Vitro Assays 1,481 citations
• Encorafenib, Binimetinib, and Cetuximab in <i>BRAF</i> V600E–Mutated Colorectal Cancer 1,481 citations
• The first high-resolution meteorological forcing dataset for land process studies over China 1,481 citations
• Simultaneously Mitigating Near-Term Climate Change and Improving Human Health and Food Security 1,480 citations
• The Treat-to-Target Trial 1,480 citations
• Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes 1,480 citations
• BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling 1,479 citations
• Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial 1,479 citations
• Depression and Coronary Heart Disease 1,478 citations
•  -Synuclein in Parkinson's Disease 1,478 citations
• Recent Advances in Petroleum Microbiology 1,478 citations
• Breaks in Sedentary Time 1,478 citations
• Laparoscopic Nephrectomy: Initial Case Report 1,478 citations
• MOTION COMPENSATED INTER-FRAME CODING FOR VIDEO CONFERENCING 1,477 citations
• Ceritinib in <i>ALK</i> -Rearranged Non–Small-Cell Lung Cancer 1,477 citations
• HRS Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis 1,477 citations
• The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints 1,476 citations
• Why do young people drink? A review of drinking motives 1,476 citations
• A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade 1,476 citations
• Nicotine Addiction 1,476 citations
• Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome 1,474 citations
• Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype 1,474 citations
• Determinants of Long-Term Survival After Major Surgery and the Adverse Effect of Postoperative Complications 1,473 citations
• Severe Hypoglycemia and Risks of Vascular Events and Death 1,473 citations
• Global vitamin D status and determinants of hypovitaminosis D 1,473 citations
• Potential of fecal microbiota for early‐stage detection of colorectal cancer 1,473 citations
• The molecular portraits of breast tumors are conserved across microarray platforms 1,472 citations
• Focus Group Interviews in Education and Psychology 1,472 citations
• Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF 1,472 citations
• Management of Abdominal Aortic Aneurysms Clinical Practice Guidelines of the European Society for Vascular Surgery 1,472 citations
• Obesity in adults: a clinical practice guideline 1,472 citations
• The International Criteria for Behçet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria 1,471 citations
• The Management of Thrombosis in the Antiphospholipid-Antibody Syndrome 1,471 citations
• Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) 1,471 citations
• Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes 1,470 citations
• Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis 1,470 citations
• Definition and diagnostic criteria of clinical obesity 1,470 citations
• Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia 1,469 citations
• Measuring mindfulness—the Freiburg Mindfulness Inventory (FMI) 1,469 citations
• Planar perovskite solar cells with long-term stability using ionic liquid additives 1,469 citations
• The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder 1,469 citations
• RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis 1,468 citations
• Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease 1,468 citations
• Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force 1,468 citations
• Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients 1,468 citations
• Trends in College Binge Drinking During a Period of Increased Prevention Efforts: Findings from 4 Harvard School of Public Health College Alcohol Study Surveys: 1993–2001 1,467 citations
• Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1) 1,467 citations
• The Psychosis High-Risk State 1,467 citations
• Impact of COVID-19 pandemic on utilisation of healthcare services: a systematic review 1,467 citations
• Positional cloning of the wheat vernalization gene <i>VRN1</i> 1,465 citations
• A gene expression database for the molecular pharmacology of cancer 1,465 citations
• Physiological changes in pregnancy 1,465 citations
• Risk of cardiovascular mortality in patients with rheumatoid arthritis: A meta‐analysis of observational studies 1,464 citations
• Prediction and Intervention in Health‐Related Behavior: A Meta‐Analytic Review of Protection Motivation Theory 1,464 citations
• A Prospective Study of the Prevalence of Primary Aldosteronism in 1,125 Hypertensive Patients 1,464 citations
• Akt Stimulates Aerobic Glycolysis in Cancer Cells 1,464 citations
• Rotenone, Paraquat, and Parkinson’s Disease 1,463 citations
• Validation of a Decision Regret Scale 1,463 citations
• A Longitudinal, Population-Based, Cohort Study of Childhood Asthma Followed to Adulthood 1,463 citations
• International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology 1,463 citations
• Early Social Attention Impairments in Autism: Social Orienting, Joint Attention, and Attention to Distress. 1,463 citations
• Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming 1,463 citations
• Patients with mental health disorders in the COVID-19 epidemic 1,463 citations
• Association of Perceived Medical Errors With Resident Distress and Empathy 1,462 citations
• Vitamin E, antioxidant and nothing more 1,462 citations
• 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines 1,462 citations
• Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome 1,461 citations
• Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients 1,461 citations
• Bivalirudin for Patients with Acute Coronary Syndromes 1,461 citations
• Eleven grand challenges in single-cell data science 1,461 citations
• Idarucizumab for Dabigatran Reversal 1,460 citations
• AHA Dietary Guidelines 1,460 citations
• Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial 1,460 citations
• Global epidemiology and outcomes of acute kidney injury 1,460 citations
• Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals 1,458 citations
• Identification of a Common Neurobiological Substrate for Mental Illness 1,458 citations
• Sudden Cardiac Arrest Associated with Early Repolarization 1,457 citations
• Human Endothelial Progenitor Cells From Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation Into Vascular Structures 1,456 citations
• NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome 1,456 citations
• American Association of Clinical Endocrinologists and American Diabetes Association Consensus Statement on Inpatient Glycemic Control 1,456 citations
• Diabetes and Cardiovascular Disease During Androgen Deprivation Therapy for Prostate Cancer 1,455 citations
• A technical guide to tDCS, and related non-invasive brain stimulation tools 1,455 citations
• Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study 1,454 citations
• Wavelet filter-based weak signature detection method and its application on rolling element bearing prognostics 1,454 citations
• Graph Neural Networks: A Review of Methods and Applications 1,454 citations
• Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial 1,453 citations
• Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma 1,452 citations
• Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness 1,452 citations
• Noncontact Anterior Cruciate Ligament Injuries: Risk Factors and Prevention Strategies 1,452 citations
• Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis 1,452 citations
• Network‐based classification of breast cancer metastasis 1,452 citations
• Adult haemophagocytic syndrome 1,451 citations
• High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response 1,450 citations
• Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis 1,450 citations
• Evolutionary and Biomedical Insights from the Rhesus Macaque Genome 1,449 citations
• Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study 1,449 citations
• The IOC consensus statement: beyond the Female Athlete Triad—Relative Energy Deficiency in Sport (RED-S) 1,449 citations
• BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection 1,449 citations
• A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer 1,448 citations
• Microstructural maturation of the human brain from childhood to adulthood 1,448 citations
• Autism genome-wide copy number variation reveals ubiquitin and neuronal genes 1,448 citations
• The Emergence of the Metabolic Syndrome with Menopause 1,448 citations
• The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria 1,448 citations
• Psychotherapy for Borderline Personality Disorder 1,448 citations
• Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy 1,447 citations
• Family income, parental education and brain structure in children and adolescents 1,447 citations
• In vivo evidence for post-adolescent brain maturation in frontal and striatal regions 1,447 citations
• The Effect of Air Pollution on Lung Development from 10 to 18 Years of Age 1,447 citations
• Scoring of patellofemoral disorders 1,447 citations
• Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease 1,447 citations
• Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage 1,446 citations
• Top-down modulation: bridging selective attention and working memory 1,446 citations
• Consensus on consensus: a synthesis of consensus estimates on human-caused global warming 1,446 citations
• Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial 1,446 citations
• Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion 1,446 citations
• The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease 1,445 citations
• The challenge of mapping the human connectome based on diffusion tractography 1,445 citations
• Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer 1,445 citations
• The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting 1,444 citations
• Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients 1,444 citations
• Coming to Terms With Risk Factors for Eating Disorders: Application of Risk Terminology and Suggestions for a General Taxonomy. 1,444 citations
• Contribution of trends in survival and coronar y-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA Project populations 1,444 citations
• Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study 1,443 citations
• Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion 1,443 citations
• Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy 1,443 citations
• Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility 1,443 citations
• ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure) 1,443 citations
• American Society of Hematology 2020 Guidelines for Management of Venous Thromboembolism: Treatment of Deep Vein Thrombosis and Pulmonary Embolism 1,443 citations
• Neurostimulation for Parkinson's Disease with Early Motor Complications 1,442 citations
• Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European community 1,442 citations
• Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension 1,442 citations
• Anti-Neutrophil Cytoplasmic Autoantibodies with Specificity for Myeloperoxidase in Patients with Systemic Vasculitis and Idiopathic Necrotizing and Crescentic Glomerulonephritis 1,441 citations
• Fifty-five per cent return to competitive sport following anterior cruciate ligament reconstruction surgery: an updated systematic review and meta-analysis including aspects of physical functioning and contextual factors 1,441 citations
• Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology 1,441 citations
• Radiofrequency Ablation in Barrett's Esophagus with Dysplasia 1,440 citations
• Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry 1,440 citations
• Screening for Prostate Cancer 1,440 citations

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