Papers.

• Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial 1,080 citations
• Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function 1,079 citations
• Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: The arthritis, diet, and activity promotion trial 1,079 citations
• An Iron-Regulated Ferric Reductase Associated with the Absorption of Dietary Iron 1,079 citations
• Continuous Intravenous Epoprostenol for Pulmonary Hypertension Due to the Scleroderma Spectrum of Disease 1,079 citations
• Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease 1,079 citations
• A developmental and genetic classification for malformations of cortical development: update 2012 1,079 citations
• The immunology of hepatocellular carcinoma 1,079 citations
• Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis 1,079 citations
• ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death 1,079 citations
• Water Manganese Exposure and Children’s Intellectual Function in Araihazar, Bangladesh 1,078 citations
• Mortality among Patients Admitted to Hospitals on Weekends as Compared with Weekdays 1,078 citations
• Solid Renal Tumors: An Analysis of Pathological Features Related to Tumor Size 1,078 citations
• Chronic stress at work and the metabolic syndrome: prospective study 1,078 citations
• Linear discriminant analysis: A detailed tutorial 1,078 citations
• Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults 1,078 citations
• Emergence of Fatal PRRSV Variants: Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark 1,077 citations
• Immunosuppressive therapy in lupus nephritis: The Euro‐Lupus Nephritis Trial, a randomized trial of low‐dose versus high‐dose intravenous cyclophosphamide 1,077 citations
• Haptic perception: A tutorial 1,076 citations
• Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study 1,076 citations
• Guidelines on eosinophilic esophagitis: evidence‐based statements and recommendations for diagnosis and management in children and adults 1,076 citations
• ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-Segment Elevation 1,076 citations
• Essential metals in health and disease 1,076 citations
• Mood Disorders in the Medically Ill: Scientific Review and Recommendations 1,075 citations
• Neurobiology of addiction 1,075 citations
• Human metabolic individuality in biomedical and pharmaceutical research 1,075 citations
• The worldwide costs of dementia 2015 and comparisons with 2010 1,075 citations
• Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis 1,075 citations
• Hand grip strength: Outcome predictor and marker of nutritional status 1,074 citations
• Obstructive Sleep Apnea Syndrome in the Sao Paulo Epidemiologic Sleep Study 1,074 citations
• Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific <i>N</i>-Nitrosamines 1,074 citations
• Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy 1,074 citations
• Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production 1,074 citations
• Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis 1,074 citations
• 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease 1,074 citations
• Type 2 diabetes 1,074 citations
• Epithelial NEMO links innate immunity to chronic intestinal inflammation 1,073 citations
• B-type natriuretic peptide in cardiovascular disease 1,073 citations
• An Overview of Plant Phenolic Compounds and Their Importance in Human Nutrition and Management of Type 2 Diabetes 1,073 citations
• Screening for Breast Cancer: US Preventive Services Task Force Recommendation Statement 1,073 citations
• Mechanisms of receptor tyrosine kinase activation in cancer 1,073 citations
• Support Vector Machine Versus Random Forest for Remote Sensing Image Classification: A Meta-Analysis and Systematic Review 1,073 citations
• The power of genetic diversity in genome-wide association studies of lipids 1,073 citations
• Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer 1,073 citations
• Collaborative care for depression and anxiety problems 1,072 citations
• Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial 1,072 citations
• Prognostic Factors in Breast Cancer 1,072 citations
• Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy 1,071 citations
• Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood from Several Countries 1,071 citations
• The Vulnerable Elders Survey: A Tool for Identifying Vulnerable Older People in the Community 1,071 citations
• Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper# 1,071 citations
• Impacts of Plastic Pollution on Ecosystem Services, Sustainable Development Goals, and Need to Focus on Circular Economy and Policy Interventions 1,071 citations
• Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study 1,070 citations
• Resistance Exercise in Individuals With and Without Cardiovascular Disease 1,070 citations
• EndoNet: A Deep Architecture for Recognition Tasks on Laparoscopic Videos 1,070 citations
• Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images 1,070 citations
• Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non–Small-Cell Lung Cancer 1,070 citations
• The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore 1,069 citations
• Radioembolization for Hepatocellular Carcinoma Using Yttrium-90 Microspheres: A Comprehensive Report of Long-term Outcomes 1,069 citations
• Estimating mean QALYs in trial‐based cost‐effectiveness analysis: the importance of controlling for baseline utility 1,069 citations
• The Effect of Myopia and Loss Aversion on Risk Taking: An Experimental Test 1,069 citations
• A small-cell lung cancer genome with complex signatures of tobacco exposure 1,069 citations
• Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020) 1,069 citations
• Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses 1,068 citations
• Psychosocial factors at work and musculoskeletal disorders 1,068 citations
• Contrast-Induced Acute Kidney Injury 1,068 citations
• Polymer surface modification by plasmas and photons 1,068 citations
• Long-range anticorrelations and non-Gaussian behavior of the heartbeat 1,068 citations
• A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 1,068 citations
• Interventions to Improve the Management of Diabetes in Primary Care, Outpatient, and Community Settings 1,068 citations
• Practice parameter: Screening and diagnosis of autism 1,068 citations
• Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study 1,068 citations
• Video-based AI for beat-to-beat assessment of cardiac function 1,068 citations
• Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins 1,067 citations
• Identification and characterization of a fibroblast marker: FSP1. 1,067 citations
• Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues 1,067 citations
• Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data 1,067 citations
• RIBBON-1: Randomized, Double-Blind, Placebo-Controlled, Phase III Trial of Chemotherapy With or Without Bevacizumab for First-Line Treatment of Human Epidermal Growth Factor Receptor 2–Negative, Locally Recurrent or Metastatic Breast Cancer 1,067 citations
• Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma 1,067 citations
• Tendon Injury and Tendinopathy 1,067 citations
• Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity 1,066 citations
• Lesion analysis of the brain areas involved in language comprehension 1,066 citations
• The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation 1,066 citations
• The proportion of missing data should not be used to guide decisions on multiple imputation 1,066 citations
• ECCO Guidelines on Therapeutics in Ulcerative Colitis: Medical Treatment 1,066 citations
• Recent advances and trends in predictive manufacturing systems in big data environment 1,065 citations
• Role of impaired gastric accommodation to a meal in functional dyspepsia 1,065 citations
• Salmonella enterica Serovar Typhimurium Exploits Inflammation to Compete with the Intestinal Microbiota 1,065 citations
• Rapid cloning of high-affinity human monoclonal antibodies against influenza virus 1,065 citations
• Validation of the Modified Checklist for Autism in Toddlers, Revised With Follow-up (M-CHAT-R/F) 1,065 citations
• Delayed Breastfeeding Initiation Increases Risk of Neonatal Mortality 1,065 citations
• Synthetic Methods for Compounds Having CF₃–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions 1,065 citations
• A randomised controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial) 1,065 citations
• Hyaluronan as an Immune Regulator in Human Diseases 1,064 citations
• Antibody-Mediated Rejection Criteria - an Addition to the Banff ’97 Classification of Renal Allograft Rejection 1,064 citations
• Bullying victimization in youths and mental health problems: ‘Much ado about nothing’? 1,064 citations
• Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders 1,064 citations
• Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial 1,064 citations
• Ultrasonographic heel measurements to predict hip fracture in elderly women: the EPIDOS prospective study 1,063 citations
• Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review 1,063 citations
• Cancer after Kidney Transplantation in the United States 1,063 citations
• Amyotrophic lateral sclerosis 1,063 citations
• LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR 1,062 citations
• Polymers with Cavities Tuned for Fast Selective Transport of Small Molecules and Ions 1,062 citations
• American Gastroenterological Association Technical Review on the Management of Barrett's Esophagus 1,062 citations
• Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis 1,062 citations
• Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy 1,062 citations
• 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines 1,062 citations
• Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease 1,062 citations
• Using Serum Creatinine To Estimate Glomerular Filtration Rate: Accuracy in Good Health and in Chronic Kidney Disease 1,061 citations
• Prognosis for Gross Motor Function in Cerebral Palsy 1,061 citations
• Management of Adult Stroke Rehabilitation Care 1,061 citations
• Angiotensin-Converting Enzyme Inhibition With Quinapril Improves Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease 1,061 citations
• Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents 1,060 citations
• Gait and Cognition: A Complementary Approach to Understanding Brain Function and the Risk of Falling 1,060 citations
• Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society 1,060 citations
• Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus 1,060 citations
• Selexipag for the Treatment of Pulmonary Arterial Hypertension 1,060 citations
• Ritonavir: An Extraordinary Example of Conformational Polymorphism 1,059 citations
• Influence of Reported Study Design Characteristics on Intervention Effect Estimates From Randomized, Controlled Trials 1,059 citations
• International Consensus Guidance Statement on the Management and Treatment of IgG4‐Related Disease 1,059 citations
• Insulin-Like Growth Factor-Binding Proteins in Serum and Other Biological Fluids: Regulation and Functions* 1,059 citations
• Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial 1,059 citations
• Detecting human coronary inflammation by imaging perivascular fat 1,059 citations
• Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline 1,059 citations
• The Familial Risk of Autism 1,058 citations
• Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy 1,058 citations
• Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care 1,058 citations
• Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer 1,058 citations
• Transatlantic robot-assisted telesurgery 1,057 citations
• BMAL1 and CLOCK, Two Essential Components of the Circadian Clock, Are Involved in Glucose Homeostasis 1,057 citations
• Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens 1,057 citations
• Attention Increases Sensitivity of V4 Neurons 1,057 citations
• Non‐coding RNAs: regulators of disease 1,057 citations
• Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition 1,057 citations
• The human imperative of stabilizing global climate change at 1.5°C 1,057 citations
• Evolutionary Genetics and Environmental Stress 1,056 citations
• The role of the anterior prefrontal cortex in human cognition 1,056 citations
• A Self-Fulfilling Prophecy 1,056 citations
• A Population of Fast Radio Bursts at Cosmological Distances 1,056 citations
• Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer 1,056 citations
• Functional Status of Elderly Adults before and after Initiation of Dialysis 1,056 citations
• Adaptation of Drosophila to temperature extremes: bringing together quantitative and molecular approaches 1,055 citations
• Adjuvant Cyclophosphamide, Methotrexate, and Fluorouracil in Node-Positive Breast Cancer — The Results of 20 Years of Follow-up 1,055 citations
• Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity 1,055 citations
• Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial 1,055 citations
• Mechanism by which metformin reduces glucose production in type 2 diabetes. 1,055 citations
• Can commercial low-cost sensor platforms contribute to air quality monitoring and exposure estimates? 1,055 citations
• The exposome and health: Where chemistry meets biology 1,055 citations
• Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. 1,054 citations
• Fractional Flow Reserve–Guided PCI for Stable Coronary Artery Disease 1,054 citations
• Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study 1,054 citations
• RETRACTED ARTICLE: Microbiome analyses of blood and tissues suggest cancerdiagnostic approach 1,054 citations
• Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) 1,054 citations
• Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology 1,053 citations
• Vitamins C and E: Beneficial effects from a mechanistic perspective 1,053 citations
• Viral dynamics in hepatitis B virus infection. 1,053 citations
• Lifetime risk of symptomatic knee osteoarthritis 1,053 citations
• Self-Assembled Hexa- <i>peri</i> -hexabenzocoronene Graphitic Nanotube 1,053 citations
• Corticosteroid Insufficiency in Acutely Ill Patients 1,053 citations
• Addressing Current Criticism Regarding the Value of Self-Report Dietary Data 1,053 citations
• Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies 1,053 citations
• Machine Learning Applications for Precision Agriculture: A Comprehensive Review 1,053 citations
• Genomewide Association Study of Leprosy 1,052 citations
• Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma 1,052 citations
• Testing technical skill via an innovative “bench station” examination 1,051 citations
• Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. 1,051 citations
• Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial 1,051 citations
• Cigarette Smoking and Infection 1,051 citations
• <i>STAT4</i> and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus 1,051 citations
• Green, circular, bio economy: A comparative analysis of sustainability avenues 1,051 citations
• Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. 1,050 citations
• Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study 1,050 citations
• Communicating sad, bad, and difficult news in medicine 1,050 citations
• Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden 1,050 citations
• The Registry of the International Society for Heart and Lung Transplantation: Thirty-fourth Adult Lung And Heart-Lung Transplantation Report—2017; Focus Theme: Allograft ischemic time 1,050 citations
• Epidemiologic Analysis with a Programmable Calculator 1,050 citations
• Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria 1,049 citations
• Understanding and Preventing Noncontact Anterior Cruciate Ligament Injuries 1,049 citations
• Cohort profile: The Norwegian Mother and Child Cohort Study (MoBa) 1,049 citations
• 2000 Update of Recommendations for the Use of Hematopoietic Colony-Stimulating Factors: Evidence-Based, Clinical Practice Guidelines 1,049 citations
• Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome 1,049 citations
• Elevated depression and anxiety symptoms among pregnant individuals during the COVID-19 pandemic 1,049 citations
• Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy 1,049 citations
• Consolidated Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) Statement: Updated Reporting Guidance for Health Economic Evaluations 1,049 citations
• Gravitationally redshifted emission implying an accretion disk and massive black hole in the active galaxy MCG–6–30–15 1,048 citations
• A New Prognostic Index and Comparison to Three Other Indices for Patients With Brain Metastases: An Analysis of 1,960 Patients in the RTOG Database 1,048 citations
• Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein 1,048 citations
• Prognostic Significance of Histopathologic Subsets in Idiopathic Pulmonary Fibrosis 1,048 citations
• The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus: The Prague C &amp; M Criteria 1,048 citations
• Development and Validation of a Brief Version of the Difficulties in Emotion Regulation Scale: The DERS-16 1,048 citations
• The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility 1,047 citations
• Renal Function, Neurohormonal Activation, and Survival in Patients With Chronic Heart Failure 1,047 citations
• Cadmium stress: an oxidative challenge 1,047 citations
• Perioperative fasting in adults and children 1,047 citations
• (–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans 1,047 citations
• Interpreting Indirect Treatment Comparisons and Network Meta-Analysis for Health-Care Decision Making: Report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: Part 1 1,047 citations
• SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse 1,047 citations
• Attention deficit hyperactivity disorder 1,047 citations
• Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest 1,047 citations

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