Protein Tyrosine Phosphatases

TopicLeading institutions, researchers & key papers

This cluster of papers explores the role of protein tyrosine phosphatases, particularly PTPN11 and SHP2, in various human health and disease conditions such as Noonan syndrome, cancer, insulin sensitivity, and MAP kinase signaling. It also delves into the redox regulation of protein tyrosine phosphatases and their implications in cell signaling pathways.

Works

IDs:OpenAlex

How has Protein Tyrosine Phosphatases's publication output changed over time?

ScholarIQpublication output · 2002–2020

Output grew0% over the shown period — from 1 works in 2002 to 1 in 2020.

2002200320042006200720082011201420162020

What are the most-cited papers on Protein Tyrosine Phosphatases?

ScholarIQmost cited works

Protein Tyrosine Phosphatases in the Human Genome

Andrés Alonso, Joanna M. Sasin, Nunzio Bottini, Ilan Friedberg, Iddo Friedberg, Andrei L. Osterman, Adam Godzik, Tony Hunter, Jack E. Dixon, Tomas Mustelin

S110447773. 20041,884 CitationsOPEN ACCESS

A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis

Ann B. Begovich, Victoria Carlton, Lee Honigberg, Steven J. Schrodi, Anand P. Chokkalingam, Heather C. Alexander, Kristin Ardlie, Qiqing Huang, Ashley M. Smith, Jill M. Spoerke, Marion Conn, Monica Chang, Sheng-Yung Chang, Randall K. Saiki, Joseph J. Catanese, Diane U. Leong, Veronica Garcia, Linda McAllister, Douglas A. Jeffery, Annette T. Lee, Franak Batliwalla, Elaine F. Remmers, Lindsey A. Criswell, Michael F. Seldin, Daniel L. Kastner, Christopher I. Amos, John J. Sninsky, Peter K. Gregersen

S134425043. 20041,510 CitationsOPEN ACCESS

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

Olivier Harismendy, Dimple Notani, Xiaoyuan Song, Nazli G Rahim, Bogdan Tanasă, Nathaniel D. Heintzman, Bing Ren, Xiang‐Dong Fu, Eric J. Topol, Michael G. Rosenfeld, Kelly A. Frazer

Nature. 2011623 Citations

Insulin-stimulated Hydrogen Peroxide Reversibly Inhibits Protein-tyrosine Phosphatase 1B in Vivo and Enhances the Early Insulin Action Cascade

Kalyankar Mahadev, Assaf Zilbering, Li Zhu, Barry J. Goldstein

S140251998. 2001512 CitationsOPEN ACCESS

Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins

Yongna Xing, Yanhui Xu, Yu Chen, Philip D. Jeffrey, Chao Yang, Zheng Lin, Zhu Li, Stefan Strack, Jeffry B. Stock, Yigong Shi

S110447773. 2006339 CitationsOPEN ACCESS